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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLRC3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3823 Official gene symbol KLRC3 Full name killer cell lectin-like receptor subfamily C, member 3 Aliases ,NKG2-E,NKG2E, Gene summary Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] Location Chromosome: 12   Locus: 12p13 Gene position 10573194 - 10564914  Map Viewer Gene orientation minus Gene size 8281 bp Gene sequence >KLRC3:complement(3325038..3333318):Length=8281 GCAGTTATCATAGAGCACAGTCCCTCACATCACACAGCTGCAGAGATGAGTAAACAAAGA GGAACCTTCTCAGAAGTGAGTCTGGCCCAGGACCCAAAGTGGCAGCAAAGGAAACCTAAA GGCAATAAAAGCTCCATTTCAGGAACCGAACAGGAAATATTCCAAGTAGAATTAAACCTT CAAAATGCTTCTCTGAATCATCAAGGGATTGATAAAATATATGACTGCCAAGGTAAAACA TTAAATATATCTTCAATGTTATTGTTCTGGGATGTGCAGTTGAATGCAGAAGGGTGAGGA AAGATTAGGGAATATTTTACACTTGTGAGAATCAGAGTTCATAAATGGGATCTAATATTC TAATATGAAATCAGAAGACTAATTTTATTCAGGCATTGTTCAACTGTAATCAACTGTAAT CTGCAATCCACTCATGGAACATTACATTTACTGAAAATGAAATGGTATATTCTGAGAGAA AGATTACTAGAGTAGATGTAGATTTAGCGGCCAGAGTTTATCATTATGTTTCCCTGTGCA TGTGGGTTCTCTAGTATGTAATTCTCTAGTATGTAATCCTAATCAACTCTCTATCTCCCC TCTCTCAGTGCCTCTATTTCTCTCCCTGCAGGTTTACTGCCACCTCCAGAAAAGCTCACT GCCGAGGTCCTAGGAATCATTTGCATTGTCCTGATGGCCACTGTGTTAAAAACAATAGTT CTTATTCCTTGTAAGCATATTCTTGAAAGATTAGAAGGGAACGTTTTACTTTAATGCTTG GAAGTGCCTCAAAATATTTCATACTGTTGAAGAATAGAACTCTTATTTTACTGTTTCTTT CAAAGATCTATTACTTCATTTATTTTTATAGAAAAAGTTAATTTTATTAAAGATTGTCCC CATTTTAAATAACACACAAAGTTTCAAAGTAAGAAACTAAACTCATTATGGTTTATCTAA ATATTACTTTTTATAAAAATCATTTTAATTTTTCTATTACAGTCCTGGAGCAGAACAATT CTTCCCCAAATACAAGAACCCAGAAAAGTACATTTTTATTTTCAAAGTTCTGATATTAGT ACAATTTGGAACCAAAATAATATGGTTATTCTGAATTTTTCACAACATAAATAACAAAAT CATTGTAGAGAACATGTGTTTATTTTTTGTGTGTAATCTATATATATGTATATACATACA CACACAAAGATATTTTCTGATTTCATAATTCAAAGGCATGCTATAGAAGAAAAGTATTTA GAAAAACTAATTTTTGAAAGTGGTTACATCAAATACTACAAGAGATGGTGAAGTTTTGTG CTAAAGTCTTTAAAAATGTTTATTTCAAAGGTCTATTACTTTATATATTTTTATAGAAAA AGTTAATTTTATTAAAGATTCTCCCCATTTTAAATAACACACAAAGTTTCAAAGTAAGAA ACTAAACTCATTATGGTTTATCTAGATATCAGTTTTTATAAAAATCATTTTAATTTTTCT ATTACAGTCCTGGAGCAGAACAATTCTTCCCCGAATGCAAGAACCCAGAAAGGTACATTT TTATTTTCAATGCTCTGATATTAGTACAATTTATATTTTGTGTCTGTTTTAAGGCATGTA AAAGAATAGTGGCATTTTTGCAGAAAATAAGCCATAAATTCAGCCATAAATATTTATAAA GAAAGATTATGAGGCAGCATTTCCTTTTCTCCAGTAAGTAGAAATACTCACTTAAAATCA TTCTACCCTCTTTCTCCCAATTAACAGAAGTCTCCTACTGCTGTGAGATGATACCAAATA AATAATTTTACTATTCTAAAAAAGCAGTTGTGTATCAGTGAGGTTCAAGACATGTGTGGA GTGTATTTTTGTTTGTTGGTTTGCTTTATATGGGAACACAATTAGGGGAGAGAGGCTAAC CCTTTTCTGTGTATGTGTGTATGACTGACTCAGTTATTAAAAAATATATACTTATAAGCC TGTAAGGATGCATAAATATGTTAAGCACATATATGTTTATACTGTTGCAAATATGTGAAC TAATTTTCATTTTTAAAAATTCATATTGGTCTAGATAGTAATTCATATCTTTATTAGCAC GTCATTGTGGCCATTGTCCTGAGGAGTGGATTACATATTCCAACAGTTGTTATTACATTG GTAAGGAAAGAAGAACTTGGGAAGAGAGTTTGCAGGCCTGTGCTTCAAAGAACTCTTCTA GTCTGCTTTGTATAGATAATGAAGAAGAAATGGTAAGATGTAAATGTTTCAAACATTTTA TGAAAAGCTTCTTTCAGTGAATAATACATTTGTAGAAAACATCCATATGTGTGTACATAT ATTTAGCTTATATATTTTCAAGTGTATGCATTATTCAGTTGATTGACTTAATAATGTTTT TAAAGTTATATACCGCTAATGTACTTTTATTTTCAGTTTTTGCTTTTTATGGAAAACCAT GCTTCTATTAATGCTTTGAATCCACAATAAATTTTACTATTTAATTTTATTGAGCATGAT ATGATCTAGTCATGCAGATTGATCACAAAGTGAATGATCTCATGTGATACAAGTGAGATC ATGAAATAAGTTTCCAGCTCTAGCAGTTCCACCCCTGTGTATGCCCTCATCACTTATCCT GACTCCTCTCCAAAACACTGTCTTGACTTTTGAAGTTATAAATAAGGTTTGCCTGTTCTT GAATTTATAAAAAACGGAATTATACAGTGTGAATTTCATGTCTGTCTTTTTCACTCCTAT CTGATATTTGTGGAATTCCTCCATATTATTGCGGTTATCTGTAGTTTGTTACTGTTCACT GCTGTACTATGTACAAAGAACACTAAGAATTCATTCTGTCTTATGTCTCTAGATGGGGAA GTGAGTCTCATGCCCTCAGGGGCAAAGAGGACCCTGGATGGTGCATTGGTAGTCGTGGGT CCCTTTCCTGATCCTCCTCACCCACAACCACCCTGGTGTCTCCTGGTATGAGAAGGAAGC ACTTTCTCTAGCTCCGTATTGGTGGCAGGTCTCCTGGTAGATCATCCTTGCCAGTGGCAC CAGCCTTGCCTGGTATTGTGGAGGGGACTCTCCTTCGATACCCTCCTCCTATTGCCAGGT TGGGTGTAGGGAAACAGCAGGCCTAGGTCACCTTCTTCTGTCGTGTGGAGGACTTAACAT GCTCACTCGGACACTTGGTTGATCCCTGATGCTAGGGTCCCAGACAATTTCATCTTTCTC TTTCCACCTTTCAGAGTTCTCCATTACTTTTGTCTTTCATTAATCCCAGAGTTTATAGTT GTTTTTAGTAGGGAGTAGCAGAGAGAGACGAGTCTACACCACCTGGCCAGGACCCCTGTT ATTCCACAAAAACCGAATCGGATAAAAATTGAGGGCTTATCTAGTTAAAGAATGGTGTGG TACCAAGGAAACCCAATCTGTAGCTTCCATGTCATTTATTTCTGAATGACAACCCCTCAA TTCCCTTCTAAATCTCCAACTCTGAGAAATATAGCACAAAAATAGATTGATTTAGTCACA GTATCTGGAGAAATGAATGCACAGTATCAGGAAACTTATTAAAACCCTTCCTGTGTTTAT TCTGTTAATTGGAGTAACTATTACATTGCAAGAATTAAAATGTCTTTATTAACATGAGAA TAAGAATGAAAGTACTAAGTATAAACGTTGAAGAGTTCATTTAAATAAAAAATTCAAACA TTTATGAAAGTTTTTGGCACTGCAAATAGTGGTTTTCAACTTTAATATATTGTTTTTGTA ATGTTTTCATAATTATTATTTAAGTGAAAATTATTTCTTTTCTTTTAGAAATTTCTGGCC AGCATTTTACCTTCCTCATGGATTGGTGTGTTTCGTAACAGCAGTCATCATCCATGGGTG ACAATAAATGGTTTGGCTTTCAAACATGAGTAAGTTGTTTTATAGGGTGCTATATAAAAA AATATAAAGGATAAATTCAGAAGAATAATATGAATAAATCTATGTGGAATCATTGATATG AAGAAAGATGTGGAAAGTTAGTGAAATGTTGATACAAATATTTTACAATAGACCATAGTA GTCCATATATGTCCACCACTCATTGGTCAGCTAGTAACTTTCTTGGTTATGAGATGGACC AGGGGTGTCTAATCTTTGGCTTCTGTGGGCCACATTGGAAGAAGAAGAGTCTTGGGCCAC ACATAAAAGACACTAACACTAACGCTAGCTGATGAGCTAAACAAAAAAATTGCAAAAATA TCTCAGAATGTTTTAAGAAAGCTTATGTATTTGTGTTGGGCCGCATTGAAAGCTTCCTGG GCCACATGCGGCCCATGGGCCGTAAGTTAGACAAGCTTGAGATGGACTATCAGGGAATTG CAGTGCTTGTTTTCATTAAAAAGTCACCCTTATTTTACTTAAGAATATCCTCAAAGCACA ATAGTAGTGCTGTTGGTATATTGCTTACAATTTTTTATTAGTAGTTATTGTTGTCAATCT CTTATTGTGCCTAATTTTTAAATTAAACTTTATCACAGTTATGAATGTGTAGAGAAAACA TAATCTCTCTATAGGTTCTGTACTATTTCAGACATTCAGTGGGGTCTTGAAACATATCCC CCGTGGATGAAGGGGGAGTACTGTATTGAGTGTTCAGAATAATGACTTTTAGTAATAGCA TATGAAAAATTTAATTACCCTTTTTCATAAAATTATTTTCTTACAGTACATGGAAAATGC TTTTGTCTCATGGGTCATTTGCATAAAATGTAACAGAATTATGGATTTTTCTCCATTACA GGATAAAAGACTCAGATCATGCTGAACGTAACTGTGCAATGCTACATGTACGTGGACTTA TATCAGACCAGTGTGGATCTTCAAGAATCATTGTGAGCATAAGCTTTAGAATTAAAGCGC TTGAGCTTGCAGTGCATCAGATAAAATTTTATATTTGTTCAAACAGAAATGATATTATGA TTGCATAAGCCTTAAAATGAATTGTGTTATTTGCTCTAATAATAAGAAAATTCCAAATCA ATTATTGAAATATAATACACACAATTACGGAAGTACAGATACCCTCGCATTTAAGTCAGG CTCATTTTGCTGAACGTGATGTTTGTGGCATTCAGGCTTCCTAAAAGTTGCATGTTATGT TGGTCAGTTTATATGAAGTATCAAGAACAAGCAAAACCATGGAGACAGAAAATAAAATAG CGTTGCTAATGCCTAAGGGAGGTTGAAATAGGAGGTGTCCACTAATTGCTAGAATGTTTC TTTGTGTCAGTGATGAAAACTTTCTAAATTTCAGTAGCAGTGATGGTTGTAACTCTGTGA ATACACTAAACATCACTGATTTTTAATCATTTTAAGTGGATGAAATTTATGCTATGTGCA CCGTACCTCAATGAAGCTGTCCAAAACAAAAATATATACTGTCCTGGGATTGCTTGAGTC TGCATTTAATCTCTAAAGTAATTTTTAAAGATTAGCTTCTTGACATTTCCATACAATATC ATATTGTGTCCTTCAATGTACTGGGTTCAATGTATGGGGTTTTCTTTAATTTCTCTCTAT CATATTATGTATTTTGGGGGTTTGAATCATACAGAAATGCAGATATTTTACATTCATGCT TTTGTAAATAGCATTCTGATTTTAATATTCCCTTTAATAACTTTTGTTACTGTAAATAGA AATACAACTGATGTCTGCATTTTCACTTATTTTACATATTTAAATCTATCATTTCAAACA GATTTTTCTGGATTTTCTATATAAACAGCAATTTTATTTTCTTTTCTTTTTCTTTTTTTT TCTTTTTTTATTATTATTATACTTTAAGTTTTAGGGTACATGTGCACAATGTGCAGGTTT GTTACATATGTATACATGTGCCATGTTGGTGTGCTGCACCCATTAACTCGTCATTTAGCA TTAGGTATATCTCCTAATGCTATCCCTCCCCCCTCCCCCCACCCCACAACAGTCCCCTGT GTGTGATGTTCCCCTGCCTGTGTCCTGCAAATAATCACACTTTTATTTTTTCTATCCATG TGCCACAACTTATTTTTTCTTCATTTATTTTCTCTGGCTAGTACTTTATATCCAGAGTTG AATAGAAGGTACAATCAAATTTTACATGTATCATATGTATCATTTTCTGGTTTTGGCAAA AAATAATTCAACATATTATTCATATTTACAAAGTTTGGTGTTTTTTTCATCATATCTTTC TTATATTGAAGTGGTTTTATAATATTCCTTTTTTCAATAGATGTTATCAATTGTAACATT TTTATTTTTTATTACTTAGAATGATATATGTTTTCTTTATACAACATTTTATAAAATAAT TTTATTTTTGTCAAATGTTAAACTAGGCTTTGTTTCCGAAACAAATCCATGCTGATCATT GTATATTGCCCCTTATAAAATATCAGTGCACATACTACTATATCTAGGGTAAGATATGTT TCTTCATCTATGTTCACAAGGATATTTGACCACGTTTTTATTTGTAGCTATGTACTTGAA AAAGTTTTGGTCTCAAGGCTATCTTGGGAAGATTTTCTGTTTCTCTATAACCTGGAAGCA TTTGTTAAGAGTACTGCTTTAGCCATAAAAAAGGATGAGTTCATGTCCTCTGCAGGGACA TGGATGAAGCTGGAAACCATCATTCTCAGCAAACTATCACAAGGACAGAAAACCAAACAC CGCATGTTCTCACTCATAGGTGGGAATTGAACAATGAGAACACATGGACACAGGGAGGAG AACATCACACACCGGGGCCTGTCGGGGGGTGGGGGGTTGGGGGAGGGATAGCATTAGGAG AAATACCTAATGTAAATGATGAGTTGATGGGTGCAGCACACCAACATGGCACATCTATGC CTATGTAACAAACCTGCACGTTGTGCACATATACCCTAGAACTTAAAATATAATAATAAT AATAAAGAGTACCGCTTTATTTTTAAATGTTATCATTCACTAGTTATGCCATCTGAGTTT GCAGGCTATTTTTGTAGAAAAGTTTATGGCTAAACTGAATTTCTTCAATACATGTAGGGT TTACTCAGATTTCTATTTGAGGTACTATATTTTGGTAATGAGCATTTCCCAGGAATTTTC TATTTCATATGGACATTAAAATGCATTGATAATATAGTTTTATTGCCTGTTTAATAACTG TAAAGACCATAATGGTATTGCCATGTTTAAACTGGGAATAAAATATCTGTGCCTTTTCAA AATCTTCCCTTAGTAGTCCTTTGTGACCATTCATCTTGATAATTTCTTTGGCCCATATGT TATTTTGACATATATTACTGAATTAAAAACCATATAAGGTTCTCAGATTTTTGTTTATTG ACTTCTGTTGTAGGTAAAATATAGTTAGAACATTTTCTATTAAACTGGAAATGTTCTTCA TCCCTTTATAAATGTGGCTCATGTGGTGAGGTACTGGTTTTAAATGTTATTTATTTTTAT TAATTAATGTTAAATTTGAATAGCTACATTTCAACTGTCTCCTAGCCAAGCTTGGCTAGC GGTACTACATTGAAATTGAGTATCCGTGTGAGTATATGTGTGTGAATGCATTCATATGAG TGATGGTTACTTGTCTAGTTTAAATCTTTCTATAGGCTCACTGGCCTGTCTTGTATTAAG CATCAAGAGAAGAGTCTTTAAAAATCCCATTTATGATTGTTTACTTGTTCACTTTATTCA ACTATATGTTGAACTTGTATCATTAGGTATATGCAATGATAAAAAATATATTACTAATGG TTTGGAAAATTAATTTATCATTATGAAGTATATTTCCCCAATTTCAGTAAATTTCATCTC GGCTCACTGCAGCCTCGACCTCACCTCCAAGGCTCAAGCGATCCTCCCACCTCAGCAACC AGAGTAGCTGGCTACAGGCCAATACCATCATGCTGGCTAATTTTCGTATTTTTTTGTAGA GACGGGGTTTCATCATGTTGACCAGGCTGGTCTTGAACTCCTGAGCTCAAGAAATCAACA CATCTTGGCCTCCCAAGTTGCTGGGATTACTGACACAAGCCACCGCCCCTGAGTGCTCAT GTACCATTTAGCTTGTGTTTTAAAAATCTACTTTTTCTGCCCTCCCTATTTTTAACTAGA TGATGTTTTAAAAATTACTTTTCCCTCTCTATATAGTTTGATTTAAGCATTAGTCATTTA CAACAAATATTAATATTAAAATGCAGACCGTTATGATTGGAAAATAAATCAATGAACAAT A OMIM ID 602892