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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLRC2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3822 Official gene symbol KLRC2 Full name killer cell lectin-like receptor subfamily C, member 2 Aliases ,CD159c,MGC138244,NKG2-C,NKG2C, Gene summary Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq] Location Chromosome: 12   Locus: 12p13 Gene position 10588592 - 10583198  Map Viewer Gene orientation minus Gene size 5395 bp Gene sequence >KLRC2:complement(3343322..3348716):Length=5395 TGCAGAGATGAATAAACAAAGAGGAACCTTCTCAGAAGTGAGTCTGGCCCAGGACCCAAA GCGGCAGCAAAGGAAACCTAAAGGCAATAAAAGCTCCATTTCAGGAACCGAACAGGAAAT ATTCCAAGTAGAATTAAATCTTCAAAATCCTTCCCTGAATCATCAAGGGATTGATAAAAT ATATGACTGCCAAGGTAAAACATTAAATATATCTTCAATATTATTGTTCTAGGATGTGCA GTTGAATGCAGAAGGGTGAGGAAAGATTAGGGAATATTTTGCACTTGTGAGAATCGGAGT TCATAATTGGGATCTAAAATTCTAATATGAAATCAGAAGACTAATTTTATTCGGGCATTG TTCAACTGTAATCTGCGGTCCACTCATGGAACATTATATTTACTGAAAATGAAATGGTAT ATTCTGAGAGAAAGATTACTAGAGTAGATGTAGATTTAGAGGCCAGAGTTTATCATTATG TTTCCCTGTGCATGTGGGTTCTCTAGTATGTAATTCTCTAGTATGTAATCCTAATCAACT CTCTATCTCCCCTCTCTCAGTGCCTCTATTTCTCTCCCTGCAGGTTTACTGCCACCTCCA GAGAAGCTCACTGCCGAGGTCCTAGGAATCATTTGCATTGTCCTGATGGCCACTGTGTTA AAAACAATAGTTCTTATTCCTTGTAAGCATATTCTTGAAAGATTAGAAGGGAACGTTTTA CTTTAATGCTTGGAAGTGCCTCAAAATATTTCATACTGTTGAAGAATAGAACTCTTATTT TACTGTTTCTTTCAAAGATCTATTACTTCATTTATTTTTATAGAAAAAGTTAATTTTATT AAAGATTGTCCCCATTTTAAATAACACACAAAGTTTCAAAGTAAGAAACTAAACTCATTA TGGTTTATCTAAATATTACTTTTTATAAAAATCATTTTAATTTTTCTGTTACAGTCCTGG AGCAGAACAATTCTTCCCCAAATACAAGAACCCAGAAAAGTACATTTTTATTTTCAAAGT TCTGATATTAGTACAATTTGGAACCAAAAGTAATATGGTTATTCTGAATTTTTCACAACA TAAATAACAAAATCATTGTAGAGAACATGTGTTTATTTTTTGTGTGTAATCTATATATAT GTATATACATACACACACAAAGATATTTTCTGATTTCATAATTCAAAGGCATGCTATAGA AGAAAAGTATTTAGAAAAACAAATTAATTTTTGAAAGTGGTTACATCAAATACTACAAGA GATGGTGAAGTTTGTGCTAAAGTCTTTAAAAATGTTTATTTCAAAGGTCTATTACTTTAT ATATTTTTATAGAAAAAGTTAATTTTATTAAAGATTCTCCCCATTTTAAATAACACACAA AGTTTCAAAGTAAGAAACTAAACTCGTTATGGTTTATCTAGATATCAGTTTTTATAAAAA TCATTTTAATTTTTCTATTACAGTCCTGGAGCAGAACAATTTTTCCCCGAATACAAGAAC GCAGAAAGGTACATTTTTATTTTCAATGTTCTGATATTAGTACAATTTATATTTTGTGTC TGTTTTAAGGCATGTAAAAGAATAGTGGCATTTTTGCAGAAAATAAGCCATAAATTCAGC CATAAATATTTATAAAGAAAGATTATGAGGCAGCATTTCCTTTTCTCCAGTGAGTAGAAA TACTCACTTAAAATCATTCTACCCTCTTTCTCCCAATTAACAGAGGTTTCCTACTGCTGT GAGATGATACCAAATAAATAATTTTACTATTCTAAAAAAGCAGTTGTGTATCAGCGATGT TCAACACATGTGTAGAGTGTATTTTTGTTTGTTCATTTGCTTTATATGGGAACACAATTA GGGAGGAGAGGCTAACCCTTGTCTGTGCATGTGTGTATGACTGACTCAGTTATTAAAAAT ATACATTTATAAGCCTGTAAGGATGCGTAAATATGTTAAGCACATATATGTTTATACTGT TGAAATATGTGAACTAATTTTCATTTTTAAAAATTCATATTGGTCTAGATAGTAATTCAT ATCTTTATTAGCACGTCATTGTGGCCATTGTCCTGAGGAGTGGATTACATATTCCAACAG TTGTTATTACATTGGTAAGGAAAGAAGAACTTGGGAAGAGAGTTTGCTGGCCTGTACTTC GAAGAACTCCAGTCTGCTTTCTATAGATAATGAAGAAGAAATGGTAAGATGTAAATGTTT CAAACATTTTATGAAAAGCTTCCTTCAGTGAATAATACATTTGTAGAAAACATCCATATG TGTGTACATATATTTATCTCATATATTTTCAAGTGTATGTAATATTCAATTGATTGACTT AATAATGTTTTTAAAGTTATATACTGCTAATGTACATTTATTTTCAGTTTTTGTTTTTCA AGGAAAACCATGCTTCTATAAGTGCTTTGAATCCACAATAAATTTTGCTATCTAATTTTA TCGGGCATGATATCATCTGGTCATGCAGATTGATCACAAAGTGAATGAATGCATGTGATA CAAGTCAGATCATGAAATAAAAGTTTCCAGCTCTAGCAGTTCCACCCCTGTGTATGCCCT CATCACTTATCCTGACTCCTCTCCAAAACGCAGTCTTGACTTTTAATATTATAAATAATG ATTGCCTGTTCTTGAATTTATTTATATAAAGGGAATCAAGCAGTGTGAATTTCATGTCTT TTTCAATCCTATCTGATATTTGTGCAATTCCTCCATATTATTGCAGTTATCAGTAGTATG TTACTGTTCACTGCTGTACTATGTACAAAGAACAGTAAGAATCCATTGAGTCCTTGTCTC TGGATGGGGAAGTGGGTCTCATGCCCTCAGGGACAAAGAGGACCCTAGGTGGTTTACGGT GCACTGTTAGTCATGGGGTCCCTTTGCTGATCCTCCTCATCCACAGCCATCCTGGTGTCT CTTGGTATGAGAAGGAAGCACTTTCTCTAGCTCCATATTGGTAGCAGGTCTCCTGGTAGA TCATCCTTGCCAGTGGCACCAGCCTTGCCTGGTATTGTGGAGGGGACTCTCCTTCGATAC CCTCCTCCTATTGCCAGGTTGGGTGTAGGGAAACAGCAGGCCTAGGTCACCTTCTTCTGT CGTGTGGAGGACTTAACATGCTCACTCGGACACTTGGTTGATCCCTGATGCTAGGGTCCC AGACAATTTCATCTTTCTCTTTCCACCTTTCAGAGTTCTCCATTGCTTTTGTCTTTCATT AATCCCAGAGTTTATAGTTGTTTTTAGTCGGGAGTAGCAGAGAGAGACGAGTCTACACCA CCTGGCCAGGACCCCTGTTATTCCGCAAAAACCGAATCGGATAAAAATTGAGGGCTTATC TAGTTAAAGAATGGTGTGGTACCCAGAAAACCCAATCTGTAGCTTCCATGTCATCTATTT CTGAATGACAACCCCTCAATTCCCTTCTAAATCTCCAACTCTGAGAAATATAGCACAAAA ATAGATTGATTTAGTCACAGTATCTGGAGGAATGAATGCACAGTATCAGGAAACTTATTA AAACCCTTCCTGCGTTTATTCTGTTAATTGGAGTAACTATTACATTGCAAGAATTAAAAT GTCTTTATTAACATGAGAATAAGAATGAAAGTACTAAGTATAAACGTTGAAGAGTTCATT TAAATAAAAAATTCAAACATTTATGAAAGTTTTTGGCACTGCAAATAGTGGTTTTCAACT TTAATATATTGTTTTTGTAATGTTTTCATAATTATTATTTAAGTGAAAATTATTTCTTTT CTTTTAGAAATTTCTGGCCAGCATTTTACCTTCCTCATGGATTGGTGTGTTTCGTAACAG CAGTCATCATCCATGGGTGACAATAAATGGTTTGGCTTTCAAACATAAGTAAGTTCTTTT GTATGGCGCTATATAAAAAATATATATAAAGGATAAATTCAGAAGAATAATATGAATAAA TTTATGTGGAATCATTGACATGAAGAAAGATGTGGAAAGTTAGTGAAATGTTGATATAAA TATTTTACAATAGACCATAGTAGTCCATATATTTCAACCGCTCATTGGTCTGCTAGTAAC CTTCTTGGTTATCAGATGGACCAGGGGTGTCCCATCTTTGGCTTCTGTGGGCCACGTTAG AAGACGAATAGTCTTGGGCCACACATAGAATACACTAACACTAACGATAGCTGACGAGCT AAAAAAAAAAAAAAAATCACAGAATGTTTTAAGAAAGTTTACGTATTTGTGTTGGGCCGC ATTCAAAGCTGTCCTGGGTCACGTGCGGCCCATGGGCAGCGAGTTGGACAACCTCGAGCT GGACTATCAGGGAACTGCAGTGCTTGTTTTTATTAAAAAGCCACGCTTACTTTTTTACTT AAGAATATCCTCAAAGCACAATAATAGTGCTGTTGGCATATTGCTATAATTTTTTTATTA TTAGTTATTGTTGTCAATCTCTTATTGTGCCTAATTTATAAATTAAACTTTATCACAGTT ATGAATGTGTAGAGAAAACATAATCTCTCTATAGGTTCTGCACTATCTGCCATTTCAGGC ATCCACTGGGGTCTTGAAACATATCCCTCGTGGATGAAGAGGGACTACTCTGTTGAGTGT TCAGAATAATGACTCTTACTAATATTATGAAAAATTTAATTACCCTTTTCCATGAAATTC TTTTCTTACAGTACATGGAAAATGCTTTCGTCTCATGAATCATTTGCTTAAAATGTAACA GAAAATGGATTTTTCTCCATTACAGGATAAAAGACTCAGATAATGCTGAACTTAACTGTG CAGTGCTACAAGTAAATCGACTTAAATCAGCCCAGTGTGGATCTTCAATGATATATCATT GTAAGCATAAGCTTTAGAAGTAAAGCATTTGCGTTTGCAGTGCATCAGATACATTTTATA TTTCTTAAAATAGAAATATTATGATTGCATAAATCTGAAAATGAATTATGTTATTTGCTC TGATACAAAAATTCTAAATCAATTATTGAAATAGGATGCACACAATTACTAAAGTACAGA CATCCTAGCATTTGTGTCGGGCTCATTTTGCTCAACATGGTATTTGTGGTTTTCAGCCTT TCTAAAAGTTGCATGTTATGTGAGTCAGCTTATAGGAAGTACCAAGAACAGTCAAACCCA TGGAGACAGAAAGTAGAATAGTGGTTGCCAATGTCTCAGGGAGGTTGAAATAGGAGATGA CCACTAATTGATAGAACGTTTCTTTGTGTCGTGATGAAAACTTTCTAAATTTCAGTAGTG GTGATGGTTGTAACTCTGCGAATATACTAAACATCATTGATTTTTAATCATTTTAAGTGC ATGAAATGTATGCTTTGTACATGACACTTCAATAAAGCTATCCAGAAAAAAAAAA OMIM ID 602891