| Entrez gene ID | | 3791 |
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| Official gene symbol | | KDR |
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| Full name | | kinase insert domain receptor (a type III receptor tyrosine kinase) |
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| Aliases | | ,CD309,FLK1,VEGFR,VEGFR2, |
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| Gene summary | | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq] |
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| Location | | Chromosome: 4 Locus: 4q11-q12 |
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| Gene position | | 55991762 - 55944426 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 47337 bp |
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| Gene sequence |
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| OMIM ID | | 191306 |
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