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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DNMT3L (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 29947 Official gene symbol DNMT3L Full name DNA (cytosine-5-)-methyltransferase 3-like Aliases ,MGC1090, Gene summary CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined. [provided by RefSeq] Location Chromosome: 21   Locus: 21q22.3 Gene position 45682099 - 45666223  Map Viewer Gene orientation minus Gene size 15877 bp Gene sequence >DNMT3L:complement(2660664..2676540):Length=15877 CCCATCTCCACCCCTCCCCTGAACCCCACTCCCCACTGAGGTCCCCAAACCCCACCCCTC ACTCCACCCTGAGGGCCCCATCCTCTGAACCCCAATCCCCCAGCCCCACTGAGCTCTTAA CCCTCCCCACCTGAGGGTTCCCTTTCCCTGCCCGTCCCCCAGCTTCCTAGCTCCCCACCC CAAGTGACCCCCCGCAGCTCCTCGCCCCTCCCACTGCAAACCGGCACTGAAGGGCTGCCC CGCCCCCGCCCCTCCCCGCCCCCGCGGGACACGCCCAGATTCTTTGCCCCCATAGCCTGG TGACCTCTGGCCACCCGCTGTCCCAGGTGGGCCTGGATCCTTCCAGCTCATTCTTTGCCT GCGCCGTCCCTCGTTCCATGGCCCAGTCCTCCCCGGGGACCCTGAGCCTGGAAGCCCCGG ACCACTGGAACCTTGAACCCACCAGCTGGCTGTACCCGGAGCCGTGGCAGCAGCCCTGTG AGTCTCTTTCCTACTCCCTGACCATGCTGCCTTCAAGGGTGCGGCTGGCCAAGACCATCC CCAGGGGTCCCTGCTGGGCCTGAGGGACACTGTAGGAGGCTGGGGCATGGGAGTCCCTGA GGGGTCGAAGGCTGGGCCCAGAGGAAAGCAGGGGCTGCAGCGGCCATTGGCCCCAGGTCC TCATGAGGGCCCTGCCCTCCCCTTTTTGCCCCATCTTCCATGTTGTAACAGGGCCAGGCA GGTGGGGGGCACGCCTCAGGGGACCCTTGAGCCCCTCTCAGGGCTGGCACTGGCCTTGGC TGTCCTGCCCCTCATCCCTGGGTTGGGCAGGTGGGTGTCACCGCGGGGGTTCAGGTGGCC TGAACTAGTCAAGGTCTGCTCAGCAAGCTGCTTCCCGTGCTGGGGTGCATCAGGGATCTG AGCAGGGGCTGACGGCTTTCTCACATCTGTGTCCGTGTGTCCTGACACAGCATCCCCATG GCGGCCATCCCAGCCCTGGACCCAGAGGCCGAGCCCAGCATGGACGTGATTTTGGTGGGA TCCAGTGAGCTCTCAAGCTCCGTTTCACCCGGGACAGGCAGAGGTGAGGGCTCATCTGCT TATTGGACCAGTCACTTAGGATGCTGATCCCAGGCCTGGATGAGGTCTGGAGTTCCAGGC TTCTGGAGTATTCATGCATTATTCAGGCACCCGGGCTGGGGCAGGAGGTTCCCCACCCAC AGTCTTCCCCCAGGTATGGGCGTTTAACACACCAAGATAAGGTGTGAGGGCGGGATGGCA GGGGACCTCAGGCTCCTGTGACTTTGGAAAACGAATTGTGATGCTCACTTCCTGGCCGAA TTTAAATTAAGAGATCAGAGGAAGAAGAAAGGGGCTACTTCTTATCTTCCTTTCCAGATC TTATTGCATATGAAGTCAAGGCTAACCAGCGAAATATAGAAGGTGAGTGTTTGCATACTG GCCCACACCAGACAAAAGAGACGGGGCACAGTGGCTCACACCTATAATCCCAGCACTTTG GGAGACCAATGTGGGAGGATCATTTGAGCCCAGGAGTTTGAGACCAGCCTAGGCAACATA GTGAGACTCTGTCTCTACAAAAAAATAAAAATAAAAATTAACCAGGCATGGTGGCATGCA CCTGTAGTCCCAGCTACTCAGGAGGCTGAGTTGGGAGGATTGCTTGAGCTGGGGAGGTCG AGGCTGCAGTGAGCTATGATAACACCACTGCACTCCAGCCTGGGTGACGGTGAGATCCTG GAAGGAGGCAGTGGACACCACTGTGCCACGTGTATCCCTTCTCCCCCTCCCAAGGCCCCT GTAGCTTCATTTAAAGCATATAGTTTAATGTATTTTAGTTTATTTACAGAGTCAGCAACC ATCATCACCATCTAATTTTAGAAGGTTTTCATCACCCTGAAAAGAAAACCCATGTCTAGT AACAGTCACTCCAAATTCCCCCTTCTTGCTTCCCTTCTTTTAACTCTAGGCAACCACTCC TCGACTTTCTCTCAACGTGGGTTTGCCTTTTCTGGATCCTTTGCATTTCCGTATGAATTT AGGATCAGCCTGTCAACTCCTGCCCAAAAGCCAGCTGGGATTTTGAGAGGGCTCTGCAGC TCCATTTGGGGACTCATGCTATTTTAACAATATTAAGTCTTCTTCTTTTTTTTTTTTTTT TTTTTTTTGAGACACACTCTCACTCTGTCCCCCAGGCTGGAGTGCAGAGGCATGATCTTG GCTCATAGCAACCTCTGTCTACCAGGTTCAAGTGATTCTCCTGCTCAGCCTCCTAAAGTG CTGGAATTACAGGCATGAGCCACCACACCCAGCCAATGTTAAATCTTCTGATCCATGAAC ATGGGATATCTTTCCATTTTGTTCCATCTTCCTTAACATCTTCCAACAATACTTTGCAGT TTTCAGTGTATAAGTCTCATATTTGTTTGGCTAAATTTATTCCTAATCGTCTGCTGTATT TGACAGCACTGGGAAAACACAGTGTGCTTTGAATGTTTCCTTTAGACATCTGCATCTGCT GCGGAAGTCTCCAGGTTCACACACAGCACCCTCTGTTTGAGGGAGGGATCTGCGCCCCAT GTAAGGTAGGCAGGGAGGCTGGGGGTGACTCCCTCATGGCCTCAGAGCAGGGATGACACA AGCCAGCCTTGCTTTGCTCCTTCCAAGGACAAGTTCCTGGATGCCCTCTTCCTGTACGAC GATGACGGGTACCAATCCTACTGCTCCATCTGCTGCTCCGGAGAGACGCTGCTCATCTGC GGAAACCCTGATTGCACCCGGTGAGGCGAGGGGCCTGCCCAGGGGGGTGAAGGGGCTGAG GACACACCCATCCTTTCAGCTACTCATTCTGGAGTGTGGGTGGATTTTCTTCCCAAATGG ATGATTTCCCTGAGAGCTTCTGATTTCTGTCTCCAATGCGTCATTTGGCATAGAGCCCTG AGCTATGGGAGGCGGGTGTCTACGGTTGGCGATTGTGATTTTTCTTTTCGGTGTTGATAT TGCCACATCGCTGTGCAGGGGAGCGATGGAAACCCCACACCCCAGGCTGCCAGTCATGAC CGGGGTGACAAGGGGTATGCTCACCCCTCAGTCGTTACTCCCTCGCCTCGGCTCCCTCCG TGGGCTCCTCTCCTCGGTCCTTCTGGGCCATCCTCGTATTTACAGCTCCCCACTCCTCAA GTTCTCTCCCCCAGCTGCTGTTGCTACATTTGGTTTTGCTGGGAGTCCCTACGCTGTTTC TGCAGGCTCGAGTTTGGGGGCAGACAGGTGGCTTAGGGGGTTCCTTGGATCTGTCATTGC CTGTGAATCCACCTCCCTGTCTTCTGCACCTGGCTCGGCTCCTGTCACTCTGCGTCTCTA GGAAGGACCGTCTCCCTCTTCCCAGTCCACCACCTGGTCTTCCCAAAGGGAGCTCCAGCG TGACTTTTCCCTCCAAAACAAGGCTCAATCAGGCCCACCTCTGCCATCCTCAGGAGAGGT GGGCTGTCATGTCCGCTGCTGTGGTTTTCTGTCTGGCCTTAGATGCTACTGCTTCGAGTG TGTGGATAGCCTGGTCGGCCCCGGGACCTCGGGGAAGGTGCACGCCATGAGCAACTGGGT GTGCTACCTGTGCCTGCCGTCCTCCCGAAGCGGGCTGCTGCAGCGTCGGAGGAAGTGGCG CAGCCAGCTCAAGGCCTTCTACGACCGAGAGTCGGTAAGGAGCCCGTGGAGGGGCAGCAC CCGGCAGCAGCAGGCCCTGACTTACGGCCTTCCCTCGGTTCCCGCTGCAGAATGCAGGCG CGCCGACGGGCACCACGGCTGCAGCCTCGGGAGCAAACACTCTTTCCTGGGTTCCTCTCC GATAGTGGCTTCCACTCGATGGTGGCTTTGGGTAAACTGCTTTGGCAGTTTTGTTGCTTC CAAGCCTAGGAACGAGGCCCTGGTAGCAGATGGGAGAGGGGCCGGGAGAGGGTGGCTGGC ACGTCTCAAAGTCCAGTCCTCAGGAGCAAGTGCCTGGGCTTCTGCTGGCCAGGTGTGGGC CGTTTTGGGAGTCCAGCCGAGGAGCCAGGGGGGCCGGCAGGAACCTCAGACAAAGGCAGA GAAGGTGGAATTTTGTCCCTCTGAGAGGGACATCCAAGTCTCCATCCCTTACCTGTGAAT GTGATCTTATTTGGAAACAGGGTTTTTGCAGATGTAATTTAGTTAAGGATCACGAGATGA GATCATTCCAGATTTAGGGTGGGCCCTCAATGCAGCGACTAGTGTCACTGTAAGAGATTT GGGAAATGGAGACGGAGAAGACAGTCACATGATGATGGAGGCAGAGACTGGAGTGAGGTG TCCACCAGCCATGGGTGCCAGCAGCCCCAGGAGCTGGGGGAGAGGCCTGGCACGTCCTTG CCTGGCGCCTTCTGAGGGAGGCACGCCTGCCGGCACACCTTCACTTCAAAACCTCTGGCC TCCTGAGCTGTGAAAGAATAATTTCTGCTGTGCCAAGTCCCCTGGTCTGTTTTTTATTTA TTTATTTATTTATTTATTTATTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCC CAGGCTGGAGTGCAGTGGCGGGATCTCGGCTCACTGCAAGCTCCGCCTCCCAGGTTCACG CCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCG GCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACAGTTTTAGCCGGGATGGTCTCG ATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTG AGCCACCGCACCGGCCTTGTTTTTTATTTTTTTATTTTTGAGATGGAGTTTTGCTCTTGC TGCCCAGGCTGGAGTGCAATGGCACCCTCTTGGCTCACTGCAACCTCGGCCTCCCGGGTT CAAGCGATTCTCCTTCCTGCCTCCTGAGTACCTGGGATTACAGGCACCGACCGCCACACC CGGCTAATTCTGTACTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTG AACTCCTGACCTCAAGTGATCCACCTGCCTCAGCCTCCCAAAATGCTGGGATGACAGGCA TGAGCCACCGGGCCCAGCCCCTCCAGTCTGTTTTAATTTGCAGGCCAGCCACGGGAAGCT CCTACAGAAGGGGTGTGGCCCCCGGTGAGGCAGCCAGCGGGGAGCAAGGGACCCCTGAGC TGACCATGAAACTGCACTGGCCTCCAGCTCACATTTGTTAAGGTTGAACGAAGTCATCTC TCCCTGCCTAGCAAGCTTCAGCCTGCTCCAATTCGAAGGAAAGGGTCAGATGGGAAGGTA TTTTATAGGAACAGAGCCTAGCACTCTGAAAGCCGAGGCCCCCGAGTTTTGGGCCTTGGG GGTTGGCCCTTTAACAGGGAGCATGTGAGGCTGGAGCTGGCTGCCCGCCTAGCCCATCAG GTTGGCAGGGTCAGGGAAAACCACAGGCCTCACCTGCCCCGAGGCTCACCTCTCCCCGGC ATCTCTGGCCTTGGGGCTCTCTTCTCCGAGGTTCTGGAAGCTGCCAGGATGAGCAAGACC AGCCTGGCCAATATGGTGAAACTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGT GGCGGGTGCCTGTGATCCCAGCTACTCGGGAGGGTGAAGCAGGAGAATCGCTTGAACCCG GGAGGCGGAAAGTTGCAGTGAGCCAAGATTGCACCATTGCACTCCAGCCTGGGTGACAGA GCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAATCAGCAAACCCCTCCACACCTAC TGTCTCTCGGCTGGAGACAGGTCAGAGCGGGAGACTGAGGCTGGAGCAGGGGGTGGAGTT GGCCTTCCTGGGGGGGCAGTGCTGGTCAGGACAGGCCCAGTCAGCCTCAGCAGGTGTGTC TTATGTGTGTCTCCGGTGAGTCTCGAGTGAGTGTTCATCCAGGGAAGAATTTTCATTGTA ACTCAAGGGCTCTGTAGCCAAGTAGCCGGCACAATGTCCTGTTTTGGTTTTTTAATAAAT AGGAGAATCCCCTTGAGATGTTCGAAACCGTGCCTGTGTGGAGGAGACAGCCAGTCCGGG TGCTGTCCCTTTTTGAAGACATCAAGAAAGGTGAGTCAGTGATGTCCCAAAGACACACAT GGAAAGATGCCTCTAAACACCTGACTGCCCCTCAGGCCACCCCCCGGGACTCCCCACCCC CTCCCCTAGACCGGCCAACTGCTGATGTCCTGTACCCTTCCCCACCCTGGGCCCATGCTA ACCCTGCACTGGGGCCTTTGGAAATGGCACTTGTCTTCTGGGCCCCGCAGGCACAGCCAA ATCCATGAAGACACTCCCTCTCCTCTGGCCGTTAGGGATGTGTCCCGCTGGGACACCCAC TAAGGCCCACAAGTGTCTCAGAGCGGCCTCATGCGGGAGCACATATCTGCCCCATGCAGC CGATCAGGAGCCTGATCCCGCAGCGCCTGCACAGCCTGTCCAAGGTCTTGCTGCCCAGGA GGGGCTGAGAAAGCCAGGGCCTCCTCCAGGGCCGTTCCAGGGCTCTGCAGCTCACACCAG CTGCAGAGTGGAGTGGACTCCACTGCTCTGTGGATTTCCTAGCCAGAGGTGACATCGCAT CCCAGAAATGCCTGGTGCTGTAATACAGTCCTTGACATCCTTTTTTTTTTTGAGGCGGAG TCTCGCTCTGTTGCCCAGGCTTGATCTCGGCTCGCTGCACCTCTGCCCCCCGGGTTCAAC CAATTCTCCTGCCTCAGCCTCCCGAGCAGCTGGGATTACAGGTGCTCACCACCACGCCCA GCTAATTTTTGTGTTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGA ACTCCTGACCTCAGGTGATCCATCCGCCTTGGACTCCCAAAATGCTGGAATTACAGGCTT GAGCGTCTGTGCCCGGCCGTGCTTGACATTCTTAAATCAATACTTGGCAATGTTTGCTTG TTTAGCTTGTTGTGAGACAAAAACCTCCATCCTTAATCCTCCTGCCACGTCATTAAAAAG ATAAAGTTGGGCGGGGTGCAGTGGCTCACACGTGTAATCCCAACAATTTGGGAGGCTGAA GTGGGCGGAACATTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACATGGTGAAACCCT GTGTCTACTAAAAATACAAAAAAATTAGCCGGGCGTGGTGGCACATGCCTGTAGTCCCAG CTACTCGGGAGGTTGAGGCAGGGGAACCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAG CCAAGATCACGCCACTGCGCTCCAGCCTGGGCGACAGAGGGAGACTCCATCTCAAAACAA CAACAACAAAAATATACAGTTGGCTCCTTAATGGTAGGAGGGTCCTCTGATCGTCCGTCA GCCTTTTCGAGTCCCTGTAGGGGCACAATCCACGCTCACCCTCTGGGCCCTTCTGGTCTC TCCCCATCCAGAGCTGACGAGTTTGGGCTTTTTGGAAAGTGGTTCTGACCCGGGACAACT GAAGCATGTGGTTGATGTCACAGACACAGTGAGGAAGGATGTGAGTACCGCCGTGAACTC TCAGACACTGTAGTGGGAGCGGGGGTGCGAGCTTCCTCAGAGGAAATGCCAAGGATGAGG CGGGCAAGGAGGCGGCAGCAGGGGCTGGGAGGAGTCCTGAACACACGGGGGCCTCTCGGC AGCCTGGTGGGGATCCTGGGTCTGACAGGAGTCAGCCCAACCCCGCCGGCCCAGCCACCA CTGTGATGCCCCGCAGCGGAGGGCTGAGCAGCACGTTTTGGTGGTCCCAGCATTGCCCAG AGCCCAGAGCCCAGAGCTCAGAGCAGGGCAGTTGGGCAAACATCTTGTCCAACATCTTGA AATCTAAGTAGCCAAATTCCACTGCCTGTGATGGGGCGCTGTCCGGCAAGGAGGGGCTGA ACCCCCACTCCACCCTCTAAAATGAGGAGGCCGAGCCTTGACCTGGACAACTGGTCACTG TTTGAAAGCATCCTCCCGCTGCTGGAAGGAGGTGACACAGCTCCAGTCGTGCGTTCCCCC TGTAGGCCAGATTCCCCGCTGCCTTGGTGCCTTCCCATGCCACTGTGAGAGAAGCATGAG CAGCCACCTGTGTACAGGTCTTTTGGGGGCTCCCGGCCTGGGACCAGCAGCCCCCCCTCA CCTCCGCTGTCCCCACCCCACCATGCCTTTTCGGCACTCGGAGACCCTCAGGTTGCACCT GCCATCAACAGTTAGGTTTATCCACTTGCTACATCGTGGAAGGACACAAAATGATGCCCC GGAGGCATGAGGAGTTTGGGGCTAATGGGATTCGGGCTGTTATGTGATTTGAGGGGGTCC AGGGAAGTGGAGTCCATTGTTGACTGGTGCTATCAGGAGACGGGGTTCTGATACTTGACT ATCTTAAGTTTTGGGGGGCTTTTTTGTTTTTTGTTTTTGAGATGGAGTCTCACTCTGTTG CCCAGGCTAGAGTGTAGTGGCACAATCTGGGCTCACTGCAACCTCCGCCTCCAGGGTTCA GGCGAGTCTCCTGCCTCAGCCTCCCAAGCAGCTGGTATTACAGGCACCCGCCACCATGCC CAGCTAATTTTTTGTATTTTTTAGTAGAGACGGGGTTTCACCATATTGGCCAGGCTGGTC TTGAACTCCTGATCTCAGGTGATCCACCCGCCTTGGCCTCCTAAAGTGCTGGGATTACAG GTGTTAGCCACCACGTCCAGCTGTTAATTTTTATTTAATAAGAATGACAGAGTGAGGGCC ATCACTGTTAATGAAGCCAGTGTTGCTCACAGCCTCCCCTTGGTCACTTTTTGTGACTGA AGGGCATGTGTTCAGGCAAGATTGTTGGGTGGCTGTGTTTTGTCTTCTTCCAGCTCGGCC ATGGAATAGCCTGTGGGGACCTACTCTGTGGTCCCCAGGGAGCTACTCTGTGGGGGCTGT TTCTGTTCAGCAGGGAAGGCTCTGCCCTTGCTGTTAGCTCCTGGAGGGCTGCGGACGGCA CCTGCTGTGTTCACAGATGACAGTTACTTCCCTAGGTAGTCTGCATGTTGGGCCTCCCAG GACTGGTTCTCTAAGGGCAATGTGAGGACAGACAGAAAAACCAAATTCTGCCAAAGTTTT TAAATAGGTTTATTCTGAGCCAATAAGAGTGACCATGGCCTGGGAAATACAGTCTTAAGA GATCCCGAGGAAGTGCACCTGAGGCGGTCAGTTACAATTTGGTTTTATGTATTTATTTAT TTTTATTTTATTTATTTATTTATTTGTTTTTGAGACGGAGGCTTGCTCTGTCGCCCAGGC TGGAGTGCAGTGGCGTGATCTCGGCTCACCGCAAGCTCCGCCTCCCGCGTTCCTGCCATT CTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCATGCCTGGCTAA TTTTTTTATATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCAATCT CCTGACCTCGTGATCCGCCCGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCC ACCACTCCCAGCACAATTGGTTTTGTACATTTCAGGGAGATGCGAACTGCAGGTGGAATC AGAAAACAGTACACGGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGAGCT GAGGAGTTCAAGACCAGTTTGAGCAACTTGGTGAAACCCCATCTCTACCAAAAATACAAA AAAGTTGGCTAGTCATGGTGATGTGCACCTGGGGTTGCTCAGGGGGCTGAGGCAGGAGGA TTGCTTGAGCCCAGGAGGTAGAGGTTGCAGTGAGCCGAGATCTCGCCATTGCACTACAGC CTGGGTGACAGAGTGAGACCCCATCTCAAAAAATCAATCAATCAATAAATCAATACATAG AAGATGTGCATTGGATCAGCCCCAAAAGGCGAGATATCTTGAAGCTTACAGGTTATAGGT GGGTTTAGGGATTCTTTAGTTGGCAGTTGGTTGAAAGAGTTGAGCTTTGCCTAAAAACTG GGAGTCAGTAGAAAGGAATGCTTGAGTTAAAATAAGGAGGTCTGCTGTCTGTCATGTGGT GCCATGGCAGAGTCACAATATACCAGGTCAAAAACACCCATTCCACAAGCTTTTGTGGTT TGTAAGGCGTGATTCCCCTACGCTCCTTAGAAAGGAATTTGAGCAAGAAAAAATAAAGGC AGAATTCAGTCCCCAAATGCATGGCACAGAGTCTTCACCTCAGACCCGGAGCTTTCTCCT CTGGGCTCCAGGCAGGCAGCCCCTGAGGCTGGTGGTGGCTGTGGATGGCTCTGCCCTAGT GGGCTCCACTCCTCAGCTTGCCCTGGCCTGTGGGCCCTGCGAGCTGAGCAGGGTCTGCCC TGGGGTCATCTCGTGCTGCCGCACGCGACCTTGCCCACTGCTGCTGCCTCTCAGTGCCCA CTCCCCTCTGTCCTGCAGGTGGAGGAGTGGGGACCCTTCGATCTTGTGTACGGCGCCACA CCTCCCCTGGGCCACACCTGTGACCGTCCTCCCAGTGAGTGATGCTTCAGTTCTGGCAGC CTGTCCCCACCACCCCTGTCTCCTCTCCTCTCTCCTCACACCTCCATGCCAGGGCAGAAA CTGCAAATTGTCAGCATTTTTCAAAAACAGCTTTATCGAGGCACCACTGACATACAGTAA GTTGCACGCATTCAGTGTGTCCGACTGGATGAGTTCTGAGCTAGCTCCACACCCATGCAC CCCTCATCAGAGTAAGAGAGCAACAGAGTAAGAGTCCCCATCACTGCAGGCTTCCCTGTG CCCCCAAGCCTCCCGCTGACCCCATGCAGCCCCCAGCGTGCCCACATCACTGCAGCTCAC GTGTCCTCTGGAGCTTCCTCTAAAAGGCGGTATTTGTGCCGCGGCACGCGCTCTGCGTCA GCTCCTCCCTCGGGGTTGCCTGTCTGTCTCTTCCCCACTCTAGGCCTGCCTGGGGGAGGA GGGGTCCATGCACCTCTGTGGCCCCAGCACTGGGCAGGGCTTCATTGCTGCTGGAGGGAC AGGGGCAGGGGGATCCCTCAGACCCAGGCCGGTGCGTCCCCTCGACCCCCTCAGCCCTTC TCTCAAGCCCCAGTTTCCTTAGGCCCCTGCCCAGATGCACCTGAACAGCGTCCCCATGAC CAGCCCCCCCGGCCCCCCCTCAGCCCTGCCCCCTCACCCCACTCCAGGCTGGTACCTGTT CCAGTTCCACCGGCTCCTGCAGTACGCACGGCCCAAGCCAGGCAGCCCCAGGCCCTTCTT CTGGATGTTCGTGGACAATCTGGTGCTGAACAAGGAAGACCTGGACGTCGCATCTCGCTT CCTGGAGGTGCGTGCAGGGCTGCGTGGGCCGCCCTCTGACCCCTGCCCACGTGAGGGAGG GGCTTTTCTGGTGGAGCTCAGTCTACACCCCAGGCTCCGGGCCTGGCTCCTTGCGGCCCC TGGTTTCCAGGTGTGTACAGGGCCCAGGAGAGCTGCTGTGCAGTCCGGGCAGGGACTGCG GCCTGGGACACAAAGCCCCTTCAAGGACAGCATGGGAGGGCAGTCCCACCTCGCACCACT CCTGTGCTCACAGAACACGGCCTCGGGGGCTCACCTCCTGCCCCTGCCCCCTCAGTCTCC ACCCACACACACGCACATCACACCACACACACAGGTGCACACACACTGCAGTGCACAGTC ACTGTACACATGCACCACACACAGGGACACACTTGCCACACACACACAGGCACACTACGT GCACACATACTCACACCACACACATACAGCCTTTTCTTCACACGTCTGAATCCTGATTGT CAGAGCAGCCACTTTTGGACTCAGCGGATGGGTCCCCTCTGGGGCTGATGGGCCGGGTGT TCCAGACACTTCCAGGGTTGGGGAGGGACGGCCACACCTCAGCCACAGGAGACAGGCGTG AGGCTCAGGAGGGGGAATTTCCTCATGCTCTCAGGTTCCATGGAGGGGCCACAGCCAGCG GGGGCCCGACCCACCGAGTGGGCAGCACCTGTGGGCCAGAGCCTTTGCTGGGGGTCCAGG TGGCGTTGAGGTTCCTTTGGTGCTGGAATCTCGTGGAGTGGCTGGAATGCAAATCCAGCT ATTCAGAAGGGGAGCAAACGCCATGAGCTGAAAATCACAAAGTCTGTGCTTTTAGAACAG GAGACTTTGTTTCTGTAAAGGGGCACAGCCTGCAAGGTCCCGTCCCCCAGGCTGGGAAGC ACGGGGCCTCCACCAAGACCAGAGGAGCCAGGAGGAGGCACTTCGAAGGGGAGGGGTGGC TGGGGCAGGAGCTCCGTGCTGACCGGGTTGGCTAAACCTGTGCGGCAGGTTATGGAGGAG CGGTGAATATTCATGAAGGGGGTCCTGCTGCGTGCGTACTGAACAAAATCCGTGGAACTT ACGACCTCTGTTCACTCCGGGGTGGAGTCTTATCATGTCAGTGTGTCGCAATGAGGCCCT AAACCTCAGAGGTCTTCTCAGGACACAGGCCCTCAAGCGCACAACCTCTGTAAACCGGCC GGAGCCAGTCTGTGGTCGGGGTCCCTTATCAGGAGGAGGTTCCTGAAGTCAGTCTCCTGC CCAGTCAGAGCTGTGGTCATGGCTGTGGAACGTGGTCAGTTGGCATCTGCAGGTGGATGA GCTGCAGTCATTTGAACCTTGCTCATCCTCATCGCGGGGCCAGTGCGTGTTTAGCCGCTG CAGAAAAAGCAGCAGCTGTGGCGTGAGGGCAGAGTCCGTCCTCTCAGTGTAGGGCACGCG GCTCGGCTCGACCCTTGCCTGGCGCGGCCTGAGGTCCTGTTTGTAATTTGATATCTTATT GCCACAGAGTCTGTTCTGTCAGTTTAAAATAATTCATCAGCATTTTTCTCCAAAGGTGAT TCATAAGAAAAAAGGACGTAGGGAACACAGTCGGGCTAGAAAGTCCATTGACCACTCAGG GCCATTGGCGGCTGAGGCCAGTGGGCCTGTGGGGGGCGCTTACCGTCCAGGTCCCCTGAC CCACGGCCGACCCTCCCGCCCCCAGATGGAGCCAGTCACCATCCCAGATGTCCACGGCGG ATCCTTGCAGAATGCTGTCCGCGTGTGGAGCAACATCCCAGCCATAAGGAGGTATTTCCT GGGCAGCTGAAAGCGTTCAGGGTCAAGGGGAACATGGACCCAGAAGCGGGGTTCACTGAG GAAATGGGGTCTGTCTAGCAGAGCCAAGCCCAGAGCAGCCTCTGCGCCCCAGTGGGACTG CGGTCGGCCTTCGGGGCCACCCTGAGACCCTGAAGACACCGAAGCCTGAGGATGCCCCTT TCCCCTTGGGGAGCTTCTCCAGCACTGGCTCTCAGCTTCTCGGGGTCCAGCCCCTGGACA CCCATATGCGCCATGGCGGCCTGGCCCTGAATCGGCTGCAGCCCCCAGGCTTTCATTCCG TGTGGCCTCCCCACCTCCCTTGCACACCCACAAGCTCATGCGTGCTCACACTCAGCCACA CTCACATGACTCACTTGCACGCTCATCCATACGCCTGTGTGCTCATGTATGCACACACAC ACAGTCATTCCCACGGTCACGCTCATCCACACACCTGTGTGCTCATGCATGCACACACAG TCATCCCCACAGTCACGCTCATCCACACACCCACATGCTCCCTCAGTCACATGCTCACAC AAGCACACTCACGACTACCACCTGCATCCACACGTTCACATGTGCTCACAATCACACAGG CACACACGCATCAGTCTCACCCACCCACACGCTTGCACCCCCTGCGGTGCACTCCTGGGC TGCCCTCCCCACCTTTTGGGGCCTTGAACACATGGCCTTTCCCCACGTGCCCTCTCTGCG GCTAAGCACCCCCTTCTGCTGCCCCCACAGCCTCTCCCAGCTGCCCCCGCCCCTCAACAG CCTTTCCAGGCGGCCCAGACCTCACGACCTCCAGCCAACCGCCCATCCATCCCCTCACTC CCACACTCGCCTGGCGTGCCTCGCTCATACGTGCATTCGTGTGGAACGAGCGCTTTCTGG CTCAGCTGAGTCATGATCTCCTCCTGCCTGAGAGTGAGTTCTGGAAACTTACTCCCTCTC ACCTCCCCGGTTCCAGCATCTCCCACGTCACCACCGAGGCACGATCCTGTTGCCTGGCAC CTGCCAAGGCATGGCACCTGCAGGTCTTGCTGGCCTGGCTTCCCCTGGATTTGAGTTTGG GTGGGGCTGAGCCGAAGCACTTTTCCAGCATGCTTTCTCTTCAGAAGCCCTCTCACCTGC ATGCCAGCCTTCGCACAGCCTCCCCCTAACCCTAAGCCTGTTCCCCGCCATGTCACTTCC TGGGAGGCCATGCCAGGCTCTGTGGGGCTGGGTGAGCGGGGGTGAAGGTGGGGGCAGACC CAGCAACACCTGTGTGCATTACAGGCCATGCCTCACCTGCTGCCTGGCCCCAGAGGCTCC TTGGCCCCCGGAGGCTCTATGCGTCCACACAGCAGTGAGAACAGCGCCCCATCAGGGTTC TTAAGTGGCAGGTGCAGCCAGACCCAGGGTTGCTGCTCCACAAAAGGCACCTCCCTCTGC TCCAGTGGCCACACTTGTGGCCCCTGCAGGCTTGGGCTGTGGGCTGGCAGCTGCTTCTTC CCAGCCCCCCTTTCTGAGCGAGGCTCCACAGAGCTCCTCACAGGGTTTCGAGGGCTGGAT CCACCTGAGCCGTGATCCTGGGGTCACCTGGTTCCCAGAAGGAGGCTGGCAGTTCCTTCC CACAGGTTTCCCTCCCAGGCTCCTGGGTGTCTCAACAGTGACATGAGAGACACCCACTCA CTGAAAGGAGAAATCCTTTTGCAGAGGTAGCCACCATCACCCCCAGGATGGTTAAGGACA GTCCCCACTGCCCTAGGGAGGGTGCCTGAGGAGGAGGAGGAGGAGGGGGACACTGTATCT GGCACTTCACTCGCAGTCTTCACCCCAAAATAAACTGAGAAATGTTCCTGGCCTCCAGTG GGGTGGCTGGGAGCAGGAGAGGGGGTGTTGGTGCCAAGTCTGCAAAGCCCGTCTTCCTCA AGGGCTCCTCACAGCAGGCTGGCAGGGGACCTTTCCTCTCACCACCTGCCCTCCTGCACC CAGGGCTGGGGCTCCCGGCACAGGCAGCCCCAGGAACCCAGGGGACGGCCTTTGTGATAG AATTCCCTGGGAATGCTCGCTGACTCTGCGAGGGTTTGGCCAACTTTTGCCCAGAGTCCT GTCCTTTCCTCTGCGGGGGTGCTGCCCAGGGATGGTGACATCCTCTAGCGATGGCCCTGG AGCTCGCTGTTCACACGGAGTGACCCCCAGCCTGCTTCCCAGGGGACCAGCCCCCGGCCG GGGGAGGCGGGAGGCAAGGGAGTCATCTGGTCCCCTGTTGCTCACTCCACCTCCATGAGA AAAACTCCCAGAATCAGGCGGGGGTTCCGGGGGGGGGGTCTTAGGCACCTGGGACAACTG AGAGGCAGGCTGTTCCCCTCGCCCCCTCGCAGCGATTCCTTCCCAGCCCCATCTCCGGGG CCACCCAGTGGGCGCTGCGCTTGCTCACAACCTTCCCTCCCCTCCTCTCAGCAGCAGGCA CTGGGCTCTGGTTTCGGAAGAAGAATTGTCCCTGCTGGCCCAGAACAAGCAGAGCTCGAA GCTCGCGGCCAAGTGGCCCACCAAGCTGGTGAAGAACTGCTTTCTCCCCCTAAGAGAATA TTTCAAGTATTTTTCAACAGAACTCACTTCCTCTTTATAAATGAGTCACTATACTGTGAA GAAAAAGACTTTTCCTAGAACAAAGGCAACTTTCCTC OMIM ID 606588