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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DPH3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID285381
Official gene symbolDPH3
Full nameDPH3, KTI11 homolog (S. cerevisiae)
Aliases,DELGIP,DELGIP1,DESR1,DPH3A,KTI11,MGC20197,ZCSL2,
Gene summaryThis gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p25.1
Gene position16306496 - 16298568  Map Viewer
Gene orientationminus
Gene size7929 bp
Gene sequence
OMIM ID608959