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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXW12 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID285231
Official gene symbolFBXW12
Full nameF-box and WD repeat domain containing 12
Aliases,FBW12,FBXO12,FBXO35,MGC120385,MGC120386,MGC120387,
Gene summaryMembers of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]
LocationChromosome: 3   Locus: 3p21.31
Gene position48413709 - 48436190  Map Viewer
Gene orientationplus
Gene size22482 bp
Gene sequence
OMIM ID609075