| Entrez gene ID | | 26223 |
| Official gene symbol | | FBXL21 |
| Full name | | F-box and leucine-rich repeat protein 21 (gene/pseudogene) |
| Aliases | | ,FBL3B,FBXL3B,FBXL3P,Fbl21,MGC120237, |
| Gene summary | | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 6 tandem leucine-rich repeats. The amino acid sequence of this protein is highly similar to that of f-box and leucine-rich repeat protein 3A. Comparisons of this gene to orthologous sequences suggest that it may be a pseudogene, and may no longer express a functional protein.[provided by RefSeq] |
| Location | | Chromosome: 5 Locus: 5q31 |
| Gene position | | 135266006 - 135277367 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 11362 bp |
| Gene sequence |
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| OMIM ID | | 609087 |
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