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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXO46 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 23403 Official gene symbol FBXO46 Full name F-box protein 46 Aliases ,20D7-FC4,FBXO34L,Fbx46, Gene summary Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM] Location Chromosome: 19   Locus: 19q13.3 Gene position 46234151 - 46213887  Map Viewer Gene orientation minus Gene size 20265 bp Gene sequence >FBXO46:complement(18482105..18502369):Length=20265 TGGGGGAAACCCGCGTAGCCGAGGGAGATGCAGCGCGCGGCGATGGTGAGAGCCCAGGCG CGGGCCGGGGGCGCTGGAGAGTCGGGACGGGGGTTCGGGACCGGGTGACGAGGGGGAAGA GGCAGGGGCGAAAGAAGGGGCTGGGTGAGGGGAGATTGCCTGGGGGAGAGGACTGGGAGG AATGGGAGCCGGAGGTAGTAGTAGAAGAATGGTGGCTTGGGGAGGGGTCTTGGAGGTGGG GTGGGAGTGGAGCTTTGGAATTGATTGTAAAGGGGCTCAGAGCTGGGGAAGTGGGCCCCG AGTTGGAGACTGGGCTGGACATCCAGGTAGAGGCCCTGAAGGGGTCGATTTCGATGGGGG CTTAACCTGCGGCGAGGGTATGAGGATCAGGGTTAGGATGAGTGAGGGGGTCTGGAAGCT CCAAGGGACAGGCGAACGGTGGACGCAATGGGTTGGGGCCTCTGGATCGGATTGGGGGCA GGAAGGCAAGTTGAGGAGGTAGGAGGGAGAAATCAGTGGTAGGATAGAGTGTGGGTTTAG GCTCCAGGACTGAGGGTGGGGTAAGGAGCGTGAAATTAGGGGCCTGGATGTAGTGATAAT TTCCCTAGTCCCGCCAGAGACTCCCGGTAAGCTGGACAGGCACAGAACTGTAGGATAATA CGGCCAGAAAGGGCCATCGAGACAGGCTTTCGCACCCTCACTTCCCCGGTGGAATTTAGA AGAGTGTAATGGTTTATCCCTATGAGAAGTACAGCATTCATATCCCCTATTCTTCCACCC CTTTGTGCCATGGACAAATCTGTGAGCCTCAGTGCCCTTATCTGTAGTATGGGAACAGCA AGCATGCCTCTGAGAACAGGGTTAAAGGGAGTCATTAAAATCGTTACTATTAGTGGGAGA GCTGGGCTGTGAAGTTTCAGTCTCAGAGCTGTTGGTGGGAAGTTCTCCGCCCCCGGAATG TGACTGGGTTACAGGTGCTAATGGATTTCCTCCTTTCCAGTCCAGTCCCAGAGGCGTTTT CTCAAAAGCTGGCACTGATCTGGGCACACACCCCAGCTCAGAAGCATGTAGGGGCTCCCC ACTGTGGATTACAGCTAACGCTTATTGTTTTACAAAATGCCTGGCCCTGTCCTTAGCTGT TTGTACACATTAACTCATTTAATTCTGATAACACCCCTGAGGGGTAGGTGCTGTTATTTT CTCCATTTTACAGAAAGGAAGCAGAAGTACAGAGAAATTAAGCAACTTTCCCAAGGCTAT CCAGCATTAATTGCTAGACTCAGGATTCCGATCTTGGCAGCCTGGCTCAGAATCTGTGCT TTCAGCACTATAATTTAGTCCTCTCTCCATACTGAAATATACAATGTGATGAGTAGAGAC AGCGAACAAAGCAGTCTAGAATATTAGTTCTGCCATTTACTTGCTATATGACCTTAGGCA AGTCTTTTATTTATTTTTATTTATTTATTTAGAGACAGTCTCCCTCTGTCACCCAGGCTG GAGTGCAGTGGTATGGCTAACTGTAGCCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCC TCAGCCTCCTGAGTAGTTGGGATTACAAGCATGTGCCACCACGCCCTGGCTAATTTTTGT AGTTTTAGTAGAGACAGGGTTTCTGCATGTTGGTCAGGCTGGTCTTGAACTCCTGGCCTC AGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTAACAGGCGTGAGCCATTGCG CCTGGCCCTATATTTATTTTTATGGTTTTTTGTTTAGTTTTGTTTTGTTTTTGAGGCGGA GTTTCGCTCTTGTTGCCCAGGCGGAGTGCAATCTTGGCTCACCGCAACCTCCGCCTCCCG GGTTCAAGCAATTCTCCGCCTCAGCCTCCCGAGTAGCTGAGATTGCAGGCATGCGCCACC ACGTCTGGTTAATTTTGTATTTTTAGTAGAGACAGGTCTTGAACTCCCGACCTCAGGTGA TCTGCCCGCCCCAGCGTCCCAAAGTGCTGGGATGACAGGCGTGAGCCACTGCGCGCAGCC TTTTTATTTTTTTAAAGACAGGGTCTCGCTCTGTTGCCCAGACAGGCTGGAATGCAGTGG CGCAATCATGACTCACTGCAGCCTCAACCTCCTGGGCTCAGGCGATCCTCCCACCTCAGC CTCCCAAGTAGCTGGGACTAATTTTTTATTACACACGGCTAATTTTTTATTTTTATTTTT GTAGAGACGCGGGTCTTACTTTGTTGCCCAGGCTGGTCTCAAATTCCTAGGCTTAAGGGG TCTTCCTGCTTCAACCTCCAAAAGTGTTGGGATTGCAGGCGTGAGCCACCACGCCTGGCC CTGGGCAAGGGTTCTTCTTTTGGGTTCTTCTCACCTATAAAATGGGATCAGTAACCCTAG GAAGGTGAGAAGTTTCGGGAAGATAATGCAGTATAGTGGAACTTACTTTATGAGCCCTTA CTCCAATACTTATGGAAGGGCTCAGTACGTGTGAGTTGTTGTTTTTGAATGTCAGTGGGA AAGAGAAGGCAGTAGAGAGGAACCAAGAGGGAAGATGTCAGGCTGTCTCCTTTCTCTCTC ATGTTGTCACCATGTCCCTGCCCTCCACCTCTGGGCTCCTAAATCCAATTACGACTTCTG GAGAGTGTGCTTACAAACTCAATCTGTGGGCTGGGCATGGTGGCTCATGCCTGTAATCCC AACACTTTGGGAGGCCATTGCGGGCAGATTGCCCGAGGCCAAGAGTTTGATCAAGACCAG CCTGGCCAACATGGCAAAACCCCATCTCTATTAGCTGGGCGTGGTGGCGGGCGCCTGTAG TCCCAGCTACTCAGGAGCCTGAGGCAGGAGAATCTCTTGAACCCAGGAGGTGGAGGTTGC AGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTGTCTCAAA AAAAAAGAACAAGGAAACTCAGTGTGTCCCCATTCCCATTCCTGTCCCCGCCAAATACCC AGTCTGGCCTTACTCCAGGTGTTTCAGTGAAGAGAAAATATTTCTAACTAGGTTTTTCTT GTTGTTGTTGTTGTTAGTTTGCTTTTGTTCGTTTAACTTTTGGGTCATTAAGGCCTCATT GGGCAGTTTGACAACTTTGTAAATTCACCTTGAAACAGTTTGGTTTATTGTGAGCTTTCT GGGCTTAATTCATTGGCTGTGATAGTAAGCTTATGGTTGAAAACACTGGCTTCAGAGAGG CGCAGGGTCAAAACCCTGCTTCTGTTGCTGTGTGACCTTGGCCAAGCTGCATTCCCACTC TGGGCCTCAGTTTTCTTTTCCCTTTTTTTTTTTTTTTGAGACAGAGTCTCACTGTTGTCC AGGCTGGAGGCCAGTGGTGTGATCTTGGCTCACTGCAATCTCCGCCTCCCGGGTTCAAAT GATGTCTTCTGCCTCAGCCTCCTGCGTAGCTGAGATTACAGGCTTGTGTCACCACGCCCA GCTAATTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATCTTGGCCAGGCTGGTCTCGA ACTCCTGACCTCAGGTGATGCACCCTCCTTGACTTCCCTAAGTGTTGGGATTACAGGCGT GAGCCACTGCTCCGACCTCTTTTTTTTTTTCTTTTTTTTTGTTTTGAACCAGGGTCTCAC TTTGTTGCCCTGGCTGGCATGCAGGGGCATCATCTTGGCTCACTGCAACTTCCACCTCCC AGGATCAAGGGATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACTACAAGCGTGTGTCA CCACACCTGCCTAATTTTTGTAGAGTCAGCGTTTCACCACGTTGCCCAGGCTGATCTTGA ACTCCTGACCTCAAGTGATCCACCCGCCTAGGCCTCCCAAAGTGCTGGGGTTACAGGCAT GAGCCCCAGTGCCCAGCCAGCCTCAGTATTCTCATGTAAAAATGGGACCACATTTAAACT CTGAGCTTCTCGTAAGGAGTTGACGTGGTAACTGATGAGGTGGCATATATAAAATGCCTG GGGTGTATTATGCTCTCAATAAGTGTGAGGTCTTTCTATGATTTTTATTCTTTCAAGAAA AGGTACTGAGGCTGGGCAAGGTGGCTCATGCTTATAATCTTGGCACTTTGGGAGGCCAAG GTGGGAGGCTGGGATTAACAGGGTGGCAGGATCAGTGGAACTCAGGAGTTTGAAATCAGC TTGGGCAACACAGGGAAAATTCATCTCTACAAACAATTTTTTTTTTTTTAGACAGTCTCG TTTTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACGTCCGCCTCT TGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTACACC TCTATGCCCTGCTAATTTTTATATTTTTAGTAGAGACGAGATTTCGTTGTGTTGGCCAGG ATGGTGCCAAACTCCTGGCCTCAAGTGATCCACCCGCCTCAACCTTCCAAAGTGCTAGAA TTACAGGTGTGAGCCACCGTGCCCAGCCATTTTTTTTGTTGTTGTTGTTAGATGGAGTCT TGCTCTGTCTCCTAGGCTGGAGTGCGGTGGTGCGATCTCAGCTCACTGCAGCCTCAACTT CCCGGGCTCAAGTGATCCTCTCACCTCAGCCTCCTGAGTATAGCTGGGACTACAGTTGCA TGCCACTACACACAGCTAATTTTTGTATCTTTTTTGTAGAGACGGGTTCTCACTATGTTG CCCAGGCTGGTCTTGAACTCCTATGCTCAAATGATCCGCCCGTCTTGGCCTTCCAAAGTG TTGAAATTACAGGCATGAGCCACTGCACCCAGCCTCAAATAAATTTTTTAAAAAATTAGT CAGGCTTGGTGGCATGAGCCTATAGTCCCAGCACCTCTGGAGGTTGAGGCGGGAGGATCA CTTGGGCCCAGGAGGTGGAAGGTGCAGTGAGCTCTGATTGCCCCATTGCACTATAGCCTG GGTGATAGAGCGAGACCATCTCAAACAAACAAACAAAAAAATCAAAGCAACAACAAAACA AAAAGAAAACAGGGAGAAAAATGCACTCTGGAGTCAGAGTGCCCAACTTTGAATCTGGAA AATGGGGTTCATTCCTTAAGTAGTCCATGTGTTTATTTATTCATTTTTATTTAAGTTTTT GAGACAAAGTCTGGCTCTATTGCCCAGGTTGGAGTGCAGTGGTACAGTCTCGGCTCCCTG CAACCTCTACCTCCCGGGCTCAAGCCATCCTCCCACCTCAGCCTTCCAAGTAGCTGGGAC TGCAGGCGCACACCACCATGCCCGGCTAATTTTTAAAAAAATTTTTGTAGAGACAGGGTT TTGCCATGTTGCCTAGGCTAGTCCTGAACAATGAGACTCAAGCTGTCGACCTGCCCAAAC TGCTGGGATTACAGGTGTGAGCCACCGCACCTGGCCCACAAGTGTTTTAGTTATTTATTT ATTTGTTCATTTATTTTTTGAGACAGGGTCTGGCTCTGTTGCCCGGGCTGGAATGCAGTG GCACTATCTTGGCTCACTGTGACTTCCACCTCCTGATCTTACGCCATCCTCTCACCTCAG CCTCCAAAATAGCTGGGACTACAGGGGCATGCCACCACACCTGGCTAATTTTTGTAATTT TTGTAGAGATGAATAATACATGCTGCCAAGGCTGGTCTCGATCTCCTGAGCTCAAGTGAT CTACCCACTTCAGCCTTCCAAAGTGCTAGAATTACAGGGTTGAGCCACCGCAGCCTATTT ATTTATTTAGAGACAGGGCCTGTCTCTGTTGCCCAGGCTGGAGTACAGTGGTGCAGTCAC AGCTTACTGCAGCCTCAAGCTCCTGGCCTCAAGTGATCCTCCTGCTTCAGCCTCCAGAGT ATCTGGGACTGCAGGTGCTTGCCACCATGCCCAGCTAATTAAAAAAAAAATTTTGTTGTT GATGGGGCACAGTGGCCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCTACATGGGCAG ATCTCTTGAGGTCAGGAGCTTGTGACCAGCCTGGCCAACACGGTGAAACCCCATCTCTAC TAAAAATACAAATTAGCCAGGCGTGGTGGCGTGTGCTTGTAGTCCCAGCTACTCGGGAGG CTGAGGCACAAGAATCACTTGAACCCCAGGAGGCGGAGGTTGCAGTGAGCTGAGATTGCA CCACTGCACTCCAGCCTGGGTAACGAGCAGGCCTCCGTCTCGAACAGAAAAAATAAGAAA TTTTTTTTTTGTAGAGACAGGGTCTTGCTATATTGCCCAGGCTGCTCTCAAACTCCTGGA CTCAAGTGATCCTCCCACTTCGGCCTCCCAAAGTGCTGGGTTACAGGCATGAGCCACAGA GCCCAGCCCACAAGTGTTAATAGAGCACTTACCATGTGCCAGCGCCTGTATTGGGTGCAG ACTCGACCCTGCCATTGGGGAACTTGCTGTTGTCATAATGGTAGGGCAGTTCTGCAAGTA TGCGAGCATTTGTGCTCATTTTCAAGTTTGGGTTTCTCTATTCCCAATTCATTTTCAGCC CCTTATGCCAGCTTGGCCTGCTTGTCACTGCTTTCATGGATTTTTTAACATTCTGTCTCC AGCCCTCATTGAATTATCTGAAAACCTATTGGTTTGGGGAAAAGTTGCCAGTCTCTCACT TGTCCCTGATCCTATGTGTCACATCTGGCCACCCTGGGGTGATCTGACACTTTTTTGTTT TCCGTTGCCTTCATTTATTTGTCTTAGAGCATTTGTCTGCTTTCCAAGTTATTTTGCCTT TTCTTGAAATCTTAAATTTGTTTTCAGCCTGTGCTTGTCTGAAGCTTACTCATACAAAAT GGTATTTTTACCATCTTTATTTCAAAACCTGTGACATGTACTAGGAAACGAAGAAAAAAA TTGTATTTTTTACCACGTTTAATGATGTATTTCTAACTGCTATGGTAAAGCTGTCTTACT CCTAAAAGCACAAGTTTTCTTTTTTTTTTCTTGAACTCCTGAGATCAGGAGTTCAAGACC AGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTG GTGGCGCACGCCTGTAGTCCCAGCTACTCGGGAGGCTGAAGCAGAAGAATTGCTTGAACC TGGGAGGCAGAGGTTGCAGTGAGCTGAGATCATGCCACTGCACTCTAGCCTGGGTGACAG AGTGAGACTGCGTCTAAGAAAAAAAAAGAAGAATTAGTTGGGCTTGGCGGCCAAGGAGGT TGAAGCTACATTGAGCTGTGACAGAACCACTGCACTCCAGCCTGGGTGACAGCGTGAGAT CATCTCAAACAAAAAGCAAAACAAAACAAAAATAAAATGAAAAAGCCAGAGTGCCCAGCT TTGAGTCCTGGCTTCACCTCTCATCAGCTGTGTGACCTAGGGTAAGTAATTTGATCCCGT TGGACGTCAGTTTCCTCCTCTGGAAAATTAGCGTTCATTCCCTAAGTAATCCACAAGTGT TTCATTCATTTATTTACTTAGAGACAGGGCCCACCTCTGTTGCCCAGGCTGGAGTGCAGT GGCATGATCATAGCTCACTGCAGCCTCACACTCCTGGGCCCAGCGGATTCTCCTGTCTCA GCCTCCCCGAGTAGCTGGAACTACAGGCTCATGCCACCATGCTCAGCCAATTTAAAAAAT TATTTTAGAGATGTGGTCTCACTTTGTTTCCCAGGCTGGTCTTGATCTCCAAGGCTCAAG CGATCCTTCTGCCCTGGCCCCCCAAAGTGCTGGGATTAAGGCATGAGTCACCACCCACAG CCTTCACTTTCAATTTTTATGTTTAATTATTTATTTTTTTGAGATGGAGTCTCCCTCTGT AGCCCAGTCTAGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCCACCTCCCAGGTT CAAGCGATTCTCCTGCCTTTGCCTCCCGAGTAGCAGGGATTATAGGCGCCTGTCACTATG CCCAACTAATTTTTTGTATTTTTAGTAGAGACAAGGTGTCACTATGTTGGCCAGGCTGGT CTCATCCTGACCTCAAGTGCCCGCTTCAGCCTCCCAAGGTGCTGGGATTACAAGCATGAG TCATCACACCCAGCCCACTTTTTTTTTTTTTTGAGACGGAGTCTGGCTCTGTCGCCCAGG CTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCAT TCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCACACCCAGCTA ATTTTTTGTATTTTTAGTAGAAACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCT CCTGACCTTGTGATCCGCCTGCCTGGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCT ACGCCTCAGTGCCAAACTGGTACCAGGTGCTCTGCTGGGTTTGTTTCAGCGGATGGTCAG CCAGCCCATGGGTGGATGCTGTCATTATTGCCATTTTACAGTGGGGGAAACTGAGGCACA TGGGGCTGAAAAACCTGCCTGAGGTCATACTGCCAGAGGTGGGAAAGCTGGGATCCAGCA GGCCCTGTCTGGTTCCTGTCTGCTTCCAGGATCTCAGGGCTTGGATGATTCCTGCCTTCA GGGACCATTAGTCAGAAAGGAAAACTTAAAAGGGAGGGGACCCAGTGGACTCTAAGGCCA ACAAGCCATGGGTGAGGTATGGATGAGTCAGGATTCTGGACAAAGGAGCAGCAGGGTAGG GCATAGAAGGAACAGGGACCGGGCGCGGTGCATCATGCCTGTAATCCCAGCACTACGGGA AGTGGGTGGATCATCTGAGATCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCC TGTCTCTACTAAAAATACGAAAATTAGCCGGGCATGGTGGCAGGTGCCTATAATCCCAGC TACTCAGGAGGCTGAGGCAGGGGAGGTGGAGGTTACAGTGAGACGAGATCGTGTTACTGC ACTCCAGCTTGGGCAACAGCACGACTCCATCTCAAAAAAAGAAAAAAAAAGGGTGGGGTG GTGCCGGGCGTGGTGGCTCACGCCTATAATCCCAGCACTTTGGGTGGATCACGAGGTCAG GAGACCGAGACCATCCTGGCTAACATGGTGAAACTCTACTAAAAATATAAATAATTAGCC GGGTGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGC TTGAACCCACGAGGCAGAGGTTCGAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGG GTGACAGAACAAGACCCTGTCAAAAAAAAAAAAAAAAAAAGGAACAGGACCAGGAACGAA ACCCTGGTGTCCTGCCACCAATTCCCATGTAACTGGGCAAGTGCCTTGTGCTGGGTGTGA CCCTGGCCCTGTGATGGGGAGCGGGGTCATCTGACTAGGGGTGGGGATGGGGAAGTGGGG TGGGGTCAGACATCTACGCTTTACCATTTATCATTATTTTTCCATTCTTTCTTTCTGTTT TGGTGTTTTTGAGCCAGGGTCTCGCTTTGGCACCCAGGCTGGAGTGCAGTGGCAAAATCT CAGCTCACTGCACCCTCCACTTCCGGGCTCAAGCGATCCTCCCACTTCAGCCTCCCGAGT AGCTGTGACTGCAGGCACATGCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTTG CCATGTTGCCCAGGCTGGTCTCAAATTCATTGGCTTAAGCGATCTGTCTGCCTCGGCTTC CCAAAGTGCTGGGATTACAGGCGCGAGCCACCACACGTGGCCTATTTTTCCTTATTTGTT TGGTTTATTCTGTTGTTTTTTTCCCCGCTTCACTTCTTTTTTTTTTTTTTTTTGGCTGAG AGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCAATCTCGGCTCATTGCAGCCAC GCCTCCTGGGTTCAAGCAATTCTCCGATTCTCCTGTCTCAAGCTCCTGAGTAGCTGGGAT TACAGGAGCCTGCCACCACATTACAGGTGTGAGCCACTGCGCCCAGCCAGGATGATGTTT ATATTGTAGTTTAGACCTTGAGCTCTGGAGTCAGCTGATCTTTGATTCTAAGTTCTGACT TGGTGTGGTTGCTCCTGCCTGTAGTCCCAGCACTTGGGGAGGCCAAGGTGGAGGATTGCT TGAGTTCAAGAGTTCAAGACTGGCCTAGGCAACATAGTGAGACCTCATCAGTACAAAAAA ATGTAAAAATTAGCTGGGCGTGCTGGTATACACCTGTGGTTTCAGCTCCTCAAAAGGCTG GGATAGGCTGGGCACAGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCTGAGGCGG GTGGATCACTTGAGGTAAGGAGTTCAAGACCAGCCTGATCAACATGGTGAAACCCTGTCT CTACTAAAAATACAAATATTAGGCCAGGTGCAGTGGCTCACGCCTGTAATCTCAACACTT TGGGAGGCCAAGGTGGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGTCTGGCCAAC ATGGTGAAACTCCATCTCTACTAAAAATGAAAAAATTATCTGGACATGGTGGCGCACACC TGTAGTCCCAGCTACTTGGGAGGCTTAGGCAAGCAAATCGCTTGAACCGGGAGGCAGAGG TTGCAGTGATTGCAGTGAGCCGAGATCGCACCGTTACACTCCAGCCTGGGCAACAGAGCA AGACTCCGTCTTAAAAAAAAAAACAAAAAAGAAGGCAGCTGAGATGGGAGGATCACTTGA GCCCAGGAGATTGAGGCTGCGTTGAGGCGAGATTGCACTCCAGCCTGGGTGACAGTGAGA CCATCTCAGAAAACAACAAAAAACAAAACACACACTCACAAAAACAGAGTTCTGCTACAA AGCTATAAATGAGGGCAATTACTTAGCCATTCTCTGCCTCAGTTTCCTTATCTTCAACAC GAAATTAAAAATAGGAGATAGAAGAATCAAACAAGTTCATATTTGTAGAGTGCTCGAGTA TTGACTGCTGTTGTGATTATCATTTTCTAATATATTCATGTTGGTTCTGACTGTTTGTTT GGATGTCTGACCCCTTTCCCATGAGCCATTCCTGGGGAGCTCAGTGTCACCTGTGTGTTC CAGCGCCCAACAATGGCCAGCATGCAGGACCACAGTGAATGTCAGAGACAAGTTTTTGCA AATGCACCATGTATGTATGTATGCTAGGGATGTAAATATGTGGATTATTTAATTGTTGGG GGCATTCAACCAAGGGTGTAGATTGAGTGGTTCAGGTCCTTACTAATTTTCCCAAGCAGT CTTTTCTTAGAAATATGTTGTTTTCCCATATCAATTGTGGATTTAACAAACTTTCCCTTG TCATTTGTAAGTTTATGGCTGTCATGTGTAGAGATGGTCGTTTTTTGCTTTATCTATTTG GAAGCCATAGTATTTGGATCATGTATGTTGAGAACTTTTGTGTATAATGGGTCACTTCCA CCTCCCTCCCCCAGCCCTAGGGACTCATGTAGAGAAGTAAATAATTGGTCATTTTGTTTC GTCATCATCCATTGCTTTTGTCAGTTTATTTATTTTTTATTTATTTAATTTATTTTTAAT TTAATTTAAGACAGTCTCGTGCTGTCACCCAGAGTGGAGTGCAGTGGCCTGATCTGAGCT CACTGCAGCCTCTACCTCCTGGGCTCAAGCAATCCTCCCACCTCAGCCTCCTGAGTACTT GGGACTACAGGCACGTGCCACCACACCCTGCTAATTTGTGTATTTTTTGTAGTGATGGGG TTTCACCATGTTGCCCAGGCTGGTCGCAGACTCCTGAGCTCAAGGGATTGTGTCCCCCCT CTGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCTGGCCAAGTTTTTTTT TTTTTTTTTTTAAGGGGTAATGTTACTCCTCTACTTGTCTCTTGGTTCGTGTTTTCCCAG CCAGTTTTTTGCCGTCTTTTGATTTTCCATATTTTTGGTTCACAATGTTTTACAATGAAT AGATTTTCATGGAGTAGTTGCTGAAGGCTGACCTAGTGTAGGGCCTTATGCTGGGCTCAG TGTGGGGGAGTTAGAAGATCCTGTCTCAGGCCTGGAGAGAGACCCACCCCAGACGATGAC CCAGAGTAGGCAGGGAAGAGGGAACCCAGAGGTCCCCTCTGGGCAGGTGGGTGATTTCCA GGAAGGGAGTTGGAGAAGGCCTCTCTAATAAAACTGCATTTGAACACAGACCTGAATGAA GTAAGGAATTGAGCCTTGCAGAGGGGGAATGTATTGCAGTTGGTGGGAACAGCAAATGCA GAGACCAGGGAAGGCAAGAGCCCGGTAACTTTGAGGAATAGACAGCAATGAGCCCACCGC ATGGACGCCCTGGGTGAAGCCTGACCTGGCCTAGGGGGATTGGGGGTGTCAGCTTCTTAG AGGAGGGGTGGTCGAGCTGAAACCCCAGGGAATATATAGTGAAACAGTAGGGCACAGTGA CTAGGAAATCAGATTCCCTGGCTTCATATCCCTGCTCCAGCTCACACTCCAGCTCTGTGT GACCTTGTGGTCAGGAGACCTGCCCTGCGTCAGTTTCTTCATCCATACCGTGGAGACGAT CACTCCTACCGGGGATCAGATGGGTCCTGAGTATTCTATGTATGCCAGATCAGGTGCCCA CCAGGGTGCACTGGGGTATTGCCTGCGGGGCGGAGGAGTGGGGAGGGATGCGACTGGACA GGTGGGGTACCTGGGTGTTTTCCAGAGGGCACTGGGGAGCCATGGCAGGTTCTCACCAGG ATAGGGACGGGTTCAGGTTTATAGGACTGTGCTTTAACAGGACTTTTCTGGCTGCTCTTT TGTACTAAGTGAGGCAGGTTTGGGGCGCCTGTTTGGAAAGGCTGAACTGGCAGCTCCGAA TGGCTACACGGCTTGAGCCTTGAACGCCAGGCCTAGAGGCTTGTTTTCAGTTGCCGTGGG AACCTTCGTAGGGTTCTGTCCATTTGTTTTTCAGGGTGGGGTTATCCCGATGCCCAATTC CCCCCGCGGAAATCCTCAGCCCGCCCCCCGCCCCCACAGTTCCCAACCAAAGCTGGATAC TCTGATCTCTCCGCCTGCTTCCTTCCGCCTTGGTGTTCTTAATCCCCGGGCTGCCTGGCC CTTTAAGTCTCAAGCGTCAATCAGGGCTTCTGTTCGAGGGGACGTGGTGTAATAAGCCTC CCCTGGAGTGTCGTGGCCTTTGCCCTGACCTTGTTCCGTTTAGCTGGACGTTGGGAGTTG TTCCACGCTCCCTTGCATCCGGCTGTGTCTACCCCACCACCCACTCCCATCACCTCTCGC CTACTCCTCCCTATTTCGAAGTTGGGCCCCTTCGCCAAGGCCTGCCTTATATGGGCACGG CCCCGAATGGCGGCCGCTCATTGGCTGAGAGCGTCACGCGCGCGTCTGTCAACAAAAGGG CGGAGGGAAGCTAGTTGCTAGTCTGCCCGCGCGGTGGCCGGAGGGAAGGAGCGAGGGGGC GGGCCCTTTTACCTTTCGCGCGCATGCGTGTGGGCTGCAGCCTTCTCCCGCCGCCTGGGG GGGCTGCGGGTGAGGGCTCTTTGGGGGCGTGTGTAGGTTTCGAGGGTCACCTGAGGGGTT TGGAAGATTTCTTTGGGGGGGCGGTTACAAGATTTGGGGGTTCCTTTTCCATTTGCAAAA TGTTCTGGGGCTTGGGGAAGTTTTAACGTGGGTTTAGGGGATACTTTTGGGGTTCTCTCG CGCTTAAGGGGCACCTTGGAGTTTGGGTTCGTTTGTAATGCGGAAGGTTCGGTTGTGTTT TCGGGATCGGGTTCCCTTTGTGTTTTGGAGTGTTTGTTGGGCATAGAATTTGGGGAGCTC CCGGAGAGACAGAAGCAAAGAGCCCGAGAGTACCAGTCCTGGAGGTGGAATGTCTGGGCT CGCGTCTTGACTTCCTACCTGTCTTAACCCGGACAGGAGATTTCACCTGTGTCTCATCGG GAACTAGGCATTAATAACACTACCTGCTTCCTAGGGACCGAGGAGGATTAGGAATTGTTA GCGCAGTACCTACCTAGTAAGCTCGCAGCGAGCGTGCAGTAAGCACATGTCTGCTATTGT AACATTTGTGAGGTTTCTTTGTTTTTTTTTTTTGGCTTTGTGAAACATTTTTATGGTTTA AGATTCATCTTAAAGTGTTAGGGAGCTTTTGTGTTTTCAAAGAGTTCGTCTGCTGTTGGA GGCTTCTAGTGGAATTGGGAGATAATGGAGGAGGGTTGGGGGGAGTATAGGATTCCGGGA GAGTGATTGTTTATGACATAGTTTGGGGAATTGCTGTGTTGGGATCTGTGAGAGATTGAC TGAGATTCGGCCCTTCAGTGCTGGAGAGGATATTTTTAGGTTCGGTGGTTTAAAGTAGTA TTTGAAAGCTTTTCGATATTTGGGGGAGGACATTGAGATGCTGGGGGTAAGGTTGGAACT GATTAGGGGACTTGAGGGGGTGGCCAGGTTGTAGCAGGATGGCATCTGTAGAGACTGGCT TTTGCTGTGTTAGCCTGCCTCCCTGGGCAGTTGGTTATACAGGTCAAGTATCCCTTACCC GAAAATCTTGGGACTAAAAAGTGTTTCGGATTTTGGATTTCTTCGGATTTTGAGTATTTG CATTATACTTATCAGTTGAGTATGCCAAGTCTGAAAAATCTGAAATGCTCTAATGAGCAT ATCCTATCAGTGTCATCTTGGCACTCAAAAAGTTCTGAATTTGGGAGCATTTTGGATTTT CAGATTTGAGATACTCAACATGTATGTGAATTGGTGGTTGGTAAACAGCCATCTATAGGT TTTGGAGGCTGTGGAGTGATATTTTTAACACTGAGCTGAGATTACAGCAGGGACTGTAAG TATTTGAGGGGTAGGTGGGATTGGGGATTATGGAGTGGAGATAAAGATTCTTGACATGGG GATTCTCTGTGTTTACTGGTACCTGTGAGTGCTTGGAGGCTGTCTGGATTTTGTTTTGTT TTCTTTCTTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTAGCTCTTGTCGCCCAGGCTGG AGTGCAGTGGCAAGATCTCAGTTCACTGCAACCTCCGCCTCCCGGTTCAAGCTATTCTCC TGCCTCAGCCTCCTGAGTAGATGGGACTACAGGCGCGCACCACCACGCCTGGCTAATTTT TGTATTTTTAGTAGAGACGGGGTTTTGCCATGTTAGCCAGGCTGATCTCGAATTCCTGAC ATCAGATGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTG TGCCAGGCCTGGAATTGTTTGAATTTAGAGGGATGGTCTGTACTGCAGGAGTTGGCAAAC TTTTTCCATAAAGAGCCAGATAATGGGTATTTTAAGCTTTGCAGGCCATGTGGTCTTTGT TCTGCTATTCAGCTCTGCTGTTGAAGATGAAAGCATCCATAAACAAATGAGCATGTTTCA ATAAAACTTTATTTACAAAGACAGCGAGCTGGATTAGGCTTCTGGGCCATAGTTTGCTGA CCTCTCTGGCCTGTAGGCATGTGGAAGTTTCAAGGTTTAAAGGGTCATTTTGGTTTTGAG CTGTCTGGAGGGAGATGAGCCAGAGAAAGATTGAGGCATATGTTACTTAGTAGGTTCAAA CTGCAGTGAAAGTGATCATGTCGGACTCATGCGCAAGATTGCCTCCAGATTAGGTCATTC ACATCAAGTCATTCCAAAATAAAATAGTCATTAACAGAGCCCTAAATTGAAGAGTCCAGA AATCAAGTTGAGAGCCTCTTTTTGCTCCGGACCCACTGTAATCTTAGCTATGTCACCCTT CCCCACTCTGAGCCTCTGTTTATCTGTGTGCAGCTTGAGGAGAAAGCTAGGCTAGAACAG GCACCCTCGTGTTTTCTTTCTTTTTTTTTCCCAAGATGGGTTCTCTCTCAGTCACCCAGG CTGGAGTGCAGTGGTATGATCACAGCATCACAGCTCACTGCAGCCTCCACCTCCTGGGCT CAAGCGATACTCCCACCTCAGCCTCCCAACTAGCTGGGACTACAGGTGCGCCACACCCCA CCCGGCTAATTTTTGTATCTTTTTTCGTAGAGATGGATTTTGCCCAGGCTGGTCTCAAAC TCCTGGGCTCAAGCAATCTGCCCACCTCGGCCTCCCAAAGTGCTAAGATTACAGGCACAA GCCACCACACCCGGCTTTGTTCTCTGTTTTTTAGAGGGTCTCACTCTGTCACCCGGGTTG GAGTGCAGTGGTGCCATCATTGCTCCCTGCAGCCTGGAACTCCTCCTAGGCTCTAGAACA GGCCCTCTTACTCCGCGGGTCCACGGCTGTGCTTTAGGGAATCCCCTGTACTGTCTTTGC AAGGGTGTGCATTTTTCTGACTGAGGACACACAGCTTTAATAAATTCTCATTAAGCCCCA CTACCTGAAAAAAAAAAAGAAAAGCCGATTTCTTAAGTGCTTGTCTGAATCTGACCTCAG ATTTTCATCCCCATCCCAGCGCATTTCGTTCCTCTCTCTGTGGGTTTAAGCAGCCATAGC TGTGGGTGGGGCTGGGAATTTCTGTCTTTTCAGGAACGAGCTACTGAGTGAGCAAATAGA AAAAGGACCTTGTCTGTCAGTGGTCCTTTCACTTAAGTGTAAAAGTTATGGCAGTTTAAA GGCCTCTGGATTGTGGGCAAAGGCAGTTGGACAGTGGGGTAGGACCTATGGGGTTGGTGC GTGCTGCCAGTTAGGGTCCCGCTCTGCAAGTTAAAAGGGCATCTCTCATCCCCTCTGCAA CCTCTGTCTGCTCACCTGAGCATGGCAGTGGGAATAGAGTTCTTTTTTTTTTTTTTTTTT TTTTTGAGACGGAGTTTCGCTCTTGTCGCCCAGGCTGGAGTGTAATGGTGCCATCTGGTC TCGCTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCGTGCCTCAGCCTCCCAAGTAGC TTGGATTACAGGCGTGGACTATCACGCCCAGCACATTTTTGTATTTTTAGTAGAGATGGG GTATCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGCCCACCTC AGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCAGGAATAGAGTT CTTGATGGTCTGGTTTGGTCTAAGGAGAGGTGGAGGTTGGGGTGGTCCTGGGAAGAAAGG CTGTCCCCCTAGCTCCCCAACCTCCTCTTCGTGTCTCCAGGTGGCATGTGGAGCCTCCCA CCACCACCTAGGTCCTGAGATGCGCTGAAGCCCAGCCTGTCTGCCATCATCCCCCAGCAT GGACCGTGGGAGCCTCCTGCCCTTCCAGCTATGGTGCCCCCGGCCCTTTGGCACCTACTC ACAGAACCAGCCACGCCCGCCTTCTGCGGCCCTCAAGCCATCAGCCTGCCCTGAGCCTGG TGGCGGGGCCGAGCCAGACCATGGGCCTGCCCACTCAGAGAACACACCACCCGCCTTGGC CACTGAGGTCCCTGCCTCCCAGCCGGCTCCGCTCCTCTCAGCAGCAGCTGCTGGTGATGA GGGTCGAGTCCTCCTGGACACGTGGTATGTCATCAAGCCCGGGAATACAAAGGAGAAGGT GGCCTTCTTTGTGGCCCACCAGTGTGGTGGGGGCAGCCGGGCCAGCTCCATGAAGGTCAA GGGGCACTGGGGCAGCGATAGCTCCAAGGCCAAGCGGCGGAGGCGCTGTCTTGACCCCAC CAAGGCTCCTCCTGACCCAGGGGGCCGGGAGGGCCCCCCTGCTGCTGAGGAGGGCCCCGC CTCAGCCGGTGAGGACGTGGACCTGCTCTCTGTGGCCGAGATGGTGGCCCTGGTGGAACA GCGGGCAGCCCTGGCCCTGCAGAGCTACCCACGACCGACCACCCCAGCGCCTGTAGTCTT TGTGTCCGCCGAGCAAGGTGGACCGGCCAAGGGGGTGGGATCTGAACGGCGGTCCGGTGG TGGGGACTGCAGCCGTGTAGCCGAGGCCGTGGCCCACTTTGAAGCGCAGAGGGACAGCCC TCCCACCAAGGGCCTCCGCAAGGAAGAGCGGCCCGGGCCAGGCCCTGGGGAGGTGCGCAT CGCCTTCCGCATCTCCAACGGCCGGGAGCCCCGTGCACCAGACAGCGGCCTGCCCAGTGG GGGCGGGGGCAGGCCTGGTTGTGCCTACCCTGGCAGCCCAGGTCCTGGGGCCCGAGCCAA GGACAAGATCACATGTGACTTATACCAGCTCATCAGCCCCTCGCGGGATGCCCTCCCCAG CAACGTGGAGTTCCTGCTGGCCAGGGCGGATGAGGCCAGTGAGGGTGACAGCCCGGCACC CGCCAGGCCTGAGGACACTCCCCCGGCGCCCCCTCCGCCCCCTGCCCGGGACTGCGGAGC GTCAGGCTTCCACGTGGACGTGGTGGTGACGGGCGTGGTAGATGAGTGCATCTTCTTTGG CAAGGACGGCACCAAGAACGTGAAGGAGGAGACTGTGTGCCTGACGGTCAGCCCGGAGGA ACCGCCGCCTCCGGGCCAGCTCTTCTTTCTCCAGAACCGCGGGCCGGACGGGCCCCCGGA GCCACCCCCGGCCGACTCCCCGGCCACTGCGCCCGGCCCAGACGATGCCGAGGGCACGGC GGACACCTCCCTGTGCCGCTTGTACCGGCACGTGTCGCACGACTTCCTAGAGATCCGCTT CAAGATTCAGCGGCTGCTGGAGCCGCGACAGTACATGCTGCTGCTGCCCGAGCACGTGCT GGTCAAGATCTTCAGCTTCCTGCCCACGCGCGCGCTGGCCGCCCTCAAGTGCACCTGCCA CCACTTCAAGGGCATCATCGAGGCGTTTGGCGTGCGGGCCACAGACTCGCGCTGGAGCCG AGACCCGCTCTACCGCGATGATCCGTGCAAACAGTGCCGCAAGAGATACGAGAAGGGCGA CGTGTCGCTCTGCCGCTGGCACCCCAAGCCCTACCACCATGACCTGCCTTACGGACGTTC CTACTGGATGTGCTGCCGTCGAGCCGACCGCGAGACTCCCGGCTGCCGCCTGGGCCTCCA CGATAACAACTGGGTGCTGCCCTGCAATGGGCCAGGCGGGGGCCGGGCCGGCCGGGAGGA GGGGAGGTGAAGCCGGGGGAGGGGAGGGGAGAGCCCACCACGCCCACCCCTCCCCTCTCC CCCCGGGAGCCGAGGGTCCGGACTGGGCCGCCTGCCCATTCCCCTACTCCAGGCAGCATT GATCCCTCACCGGAACTGAGCTGGGGTTCAGCAGGGGTGACCCAGGAAAGCCCTCTGCTT GATCCTGTTGATTTTCTACTCTTCAGAACCAGGGCCGTGGACCCTCTGAGAAGGGTGTTT TTTTTTTTTTTATCAGCATCTCACTTTCTTCTCCATTCAGCCCCAACCCCCTCCCTGCCA TGCTTTCCACCCCAAGGACCCACCAGCAGGGAGCAGACGGCAGCTAATTTTGGTACCACT TAAGGGTCCCCCCATTCTGGCCCCCATCCTCTCCCTCACCCCAATTCTTTCTCGCTGGAG CTGTTATTTCCCAAGAAGCCGCATCGCCCAAGGTTGGCACCTCTCCTAACCTGCCACACG ACAGCTCTCACCTCTCTAGGAATTGGGGGCTGTCAGGTCACAGGTGGGATCTGGCATTTT TTTATGACAGTCCATTTCTAGATGGTTTGCCTATTAAAGAAGTGGGGGGGAAATACTGTT TTCTCCTTAACCTCAAGCTACCAGTCTCTCCTCTTCCGCGTAGAGGAAGAGGGGGGCAGA CAAAAAAAAAGCTGAAGTATAAAAACCCTCCTCCTCCCGTTATTATTTAAGCTACTGCCA TCAACCCCACCCCCATAAAGCTGTGAAGCCCTTTGCCTCGCTTTTGACAGCGTGGGGGGG CCCCGTGGGCAGGGACTTCGGATTTGCATTTCTGGGTTGTTTTTCCTTCCACTCTGGGGT CTCGTTCAGGCATTGGGGTCTCCTCACCCCAGCCACATGTTTCTTTAAGAATCCTTTGGT CAACCAGGACCTTGATTTTTCAGGCATTTTGGTCTGGGGTATTTTTGTTTGTTCTCTCTG TTTTTTGTTTTCTTTTTTTTCTTTCCATCGTGGTTCTGGAAGCTTCTAGCGTGTGGCATC TGACCAATTTTGAATTGGTCCTTTCTATAAAATCAATATTTATAA OMIM ID 609117