| Entrez gene ID | | 2204 |
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| Official gene symbol | | FCAR |
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| Full name | | Fc fragment of IgA, receptor for |
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| Aliases | | ,CD89, |
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| Gene summary | | This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 19 Locus: 19q13.2-q13.4 |
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| Gene position | | 55385549 - 55401839 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 16291 bp |
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| Gene sequence |
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| OMIM ID | | 147045 |
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