| Entrez gene ID | | 2195 |
| Official gene symbol | | FAT1 |
| Full name | | FAT tumor suppressor homolog 1 (Drosophila) |
| Aliases | | ,CDHF7,CDHR8,FAT,ME5,hFat1, |
| Gene summary | | This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq] |
| Location | | Chromosome: 4 Locus: 4q35 |
| Gene position | | 187644987 - 187508937 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 136051 bp |
| Gene sequence |
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| OMIM ID | | 600976 |
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