| Entrez gene ID | | 2046 |
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| Official gene symbol | | EPHA8 |
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| Full name | | EPH receptor A8 |
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| Aliases | | ,EEK,EK3,HEK3,KIAA1459, |
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| Gene summary | | This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq] |
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| Location | | Chromosome: 1 Locus: 1p36.12 |
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| Gene position | | 22890004 - 22930087 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 40084 bp |
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| Gene sequence |
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| OMIM ID | | 176945 |
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