| Entrez gene ID | | 1791 |
| Official gene symbol | | DNTT |
| Full name | | deoxynucleotidyltransferase, terminal |
| Aliases | | ,TDT, |
| Gene summary | | This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq] |
| Location | | Chromosome: 10 Locus: 10q23-q24 |
| Gene position | | 98064085 - 98098321 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 34237 bp |
| Gene sequence |
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| OMIM ID | | 187410 |
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