Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DEFA6 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1671 Official gene symbol DEFA6 Full name defensin, alpha 6, Paneth cell-specific Aliases ,DEF6,HD-6, Gene summary Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq] Location Chromosome: 8   Locus: 8pter-p21 Gene position 6783598 - 6782219  Map Viewer Gene orientation minus Gene size 1380 bp Gene sequence >DEFA6:complement(6772219..6773598):Length=1380 ACACATCTGCTCCTGCTCTCTCTCCTCCAGCGACCCTAGCCATGAGAACCCTCACCATCC TCACTGCTGTTCTCCTCGTGGCCCTCCAGGCCAAGGCTGAGCCACTCCAAGCTGAGGATG ATCCACTGCAGGCAAAAGCTTATGAGGCTGATGCCCAGGAGCAGCGTGGGGCAAATGACC AGGACTTTGCCGTCTCCTTTGCAGAGGATGCAAGCTCAAGTCTTAGAGCTTTGGGTAAGA GACACCAGCATTGCAGAGCTAGGAGTGTAGAGAGGAAAACCAAGCACTTCTAGAATTAGA TCCAACAGCTGGCTCTTTCTCTTAGGTGATCACCTCCCCAGGCCTCAATTACTTTATGTT TGTACTGAAAAGGAAGAATCAGTGATATTCAAGGCATGACTTTTCTCTAAAGATTTTTTA ATTCTATGATAAGTCTATGAAATTTTCTAATTTTTTGCCATGTAGAAATGTATTGAGGAG TCTCTACTTCAAGGAAGAGAGCCTAATTTTAAAGGAATGTTTTGTTTTGCTTTGTTTTGT TTTGTTTTGTTTGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACTATCT CAGATCACTGCAACCTCTGCCTCCTGGGTTCACGCAATTCTCTCCCTCAGCCTCCCAAGT CACTAGGATTACAGGCACCAGACACCAAGCCTGGCTAAATTTTGTATTTTTTTTTTTTTC AGTAGAGACGGGGTTTCACCATCTTGGCCAGGCTAGTCTTGAACTCCTGACCTTGTGATA AACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCACCACATCCAGCTGC TAAAGGAATGTTTTTTAATCTGACTTTTATAGGAACCGTTGCAAACTGGAGACAGTCATA TGGGTGCATTCAGATGTGTGTGTGACAGGGAAGGAGCAGATAAGTACAGCATATCAGAAT GGCTCTCTAATCCTGTGTGTGACCAACACTGCTCTGCGTATTTATTCCTATTGATGGTGT GATCATGCTATTGGCTGTAATGCAGCCAGCATTACATGTCAGCAAGCATGCAACTTCCTG AAGATTCTCTTTACTGCCCGCTGCTGACCCTGGTGCTCAATTTCTGATGCTCTCTCTCTC TGTCCCCAGGCTCAACAAGGGCTTTCACTTGCCATTGCAGAAGGTCCTGTTATTCAACAG AATATTCCTATGGGACCTGCACTGTCATGGGTATTAACCACAGATTCTGCTGCCTCTGAG GGATGAGAACAGAGAGAAATATATTCATAATTTACTTTATGACCTAGAAGGAAACTGTCG TGTGTCCTATACATTGCCATCAACTTTGTTTCCTCATCTCAAATAAAGTCCTTTCAGCAA OMIM ID 600471