| Entrez gene ID | | 1608 |
| Official gene symbol | | DGKG |
| Full name | | diacylglycerol kinase, gamma 90kDa |
| Aliases | | ,DAGK3,DGK-GAMMA,MGC104993,MGC133330, |
| Gene summary | | This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| Location | | Chromosome: 3 Locus: 3q27.2-q27.3 |
| Gene position | | 186080023 - 185864990 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 215034 bp |
| Gene sequence |
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| OMIM ID | | 601854 |
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