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Gene information for DGKG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1608
Official gene symbolDGKG
Full namediacylglycerol kinase, gamma 90kDa
Aliases,DAGK3,DGK-GAMMA,MGC104993,MGC133330,
Gene summaryThis gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q27.2-q27.3
Gene position186080023 - 185864990  Map Viewer
Gene orientationminus
Gene size215034 bp
Gene sequence
OMIM ID601854