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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLF12 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11278
Official gene symbolKLF12
Full nameKruppel-like factor 12
Aliases,AP-2rep,AP2REP,HSPC122,
Gene summaryActivator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 13   Locus: 13q22
Gene position74708066 - 74260149  Map Viewer
Gene orientationminus
Gene size447918 bp
Gene sequence
OMIM ID607531