| Entrez gene ID | | 11258 |
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| Official gene symbol | | DCTN3 |
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| Full name | | dynactin 3 (p22) |
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| Aliases | | ,DCTN-22,DCTN22,MGC111190, |
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| Gene summary | | This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq] |
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| Location | | Chromosome: 9 Locus: 9p13 |
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| Gene position | | 34620496 - 34613548 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 6949 bp |
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| Gene sequence |
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| OMIM ID | | 607387 |
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